Simonian AP - Search Results

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[Leishmania donovani: structural insignt in the recognition of C-methylated analogues of spermidine as natural polyamine].

Mandal S, Khomutov MA, Simonian AP, Kochetkov SN, Madhubala R. Mandal S, et al. Among authors: simonian ap. Mol Biol (Mosk). 2011 Jul-Aug;45(4):673-8. Mol Biol (Mosk). 2011. PMID: 21954600 Russian.

The use of novel C-methylated spermidine derivatives to investigate the regulation of polyamine metabolism.

Hyvönen MT, Keinänen TA, Khomutov M, Simonian A, Weisell J, Kochetkov SN, Vepsäläinen J, Alhonen L, Khomutov AR. Hyvönen MT, et al. J Med Chem. 2011 Jul 14;54(13):4611-8. doi: 10.1021/jm200293r. Epub 2011 Jun 3. J Med Chem. 2011. PMID: 21639123

Unforeseen Possibilities To Investigate the Regulation of Polyamine Metabolism Revealed by Novel C-Methylated Spermine Derivatives.

Khomutov M, Hyvönen MT, Simonian A, Formanovsky AA, Mikhura IV, Chizhov AO, Kochetkov SN, Alhonen L, Vepsäläinen J, Keinänen TA, Khomutov AR. Khomutov M, et al. J Med Chem. 2019 Dec 26;62(24):11335-11347. doi: 10.1021/acs.jmedchem.9b01666. Epub 2019 Dec 13. J Med Chem. 2019. PMID: 31765147 Free PMC article.

Effects of novel C-methylated spermidine analogs on cell growth via hypusination of eukaryotic translation initiation factor 5A.

Hyvönen MT, Keinänen TA, Khomutov M, Simonian A, Vepsäläinen J, Park JH, Khomutov AR, Alhonen L, Park MH. Hyvönen MT, et al. Amino Acids. 2012 Feb;42(2-3):685-95. doi: 10.1007/s00726-011-0984-1. Epub 2011 Aug 23. Amino Acids. 2012. PMID: 21861168 Free PMC article.

Novel CoA-polyamine conjugates for effective inhibition of spermine/spermidine-N1-acetyltransferase.

Simonian A, Khomutov A, Hyvonen T, Grigorenko N, Keinanen T, Vepsalainen J, Alhonen L, Janne J. Simonian A, et al. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1245-8. doi: 10.1080/15257770701528214. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066761

A rapid and robust assay for the determination of the amino acid hypusine as a possible biomarker for a high-throughput screening of antimalarials and for the diagnosis and therapy of different diseases.

Kaiser A, Khomutov AR, Simonian A, Agostinelli E. Kaiser A, et al. Amino Acids. 2012 May;42(5):1651-9. doi: 10.1007/s00726-011-0859-5. Epub 2011 Mar 1. Amino Acids. 2012. PMID: 21360085

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