Garcia-Marcos M - Search Results

1

Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration.

Lin C, Ear J, Pavlova Y, Mittal Y, Kufareva I, Ghassemian M, Abagyan R, Garcia-Marcos M, Ghosh P. Lin C, et al. Sci Signal. 2011 Sep 27;4(192):ra64. doi: 10.1126/scisignal.2002049. Sci Signal. 2011. PMID: 21954290 Free PMC article.

2

Activation of Galphai3 triggers cell migration via regulation of GIV.

Ghosh P, Garcia-Marcos M, Bornheimer SJ, Farquhar MG. Ghosh P, et al. J Cell Biol. 2008 Jul 28;182(2):381-93. doi: 10.1083/jcb.200712066. J Cell Biol. 2008. PMID: 18663145 Free PMC article.

3

GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling.

Garcia-Marcos M, Ghosh P, Farquhar MG. Garcia-Marcos M, et al. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3178-83. doi: 10.1073/pnas.0900294106. Epub 2009 Feb 11. Proc Natl Acad Sci U S A. 2009. PMID: 19211784 Free PMC article.

4

A structural determinant that renders G alpha(i) sensitive to activation by GIV/girdin is required to promote cell migration.

Garcia-Marcos M, Ghosh P, Ear J, Farquhar MG. Garcia-Marcos M, et al. J Biol Chem. 2010 Apr 23;285(17):12765-77. doi: 10.1074/jbc.M109.045161. Epub 2010 Feb 15. J Biol Chem. 2010. PMID: 20157114 Free PMC article.

5

A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate.

Ghosh P, Beas AO, Bornheimer SJ, Garcia-Marcos M, Forry EP, Johannson C, Ear J, Jung BH, Cabrera B, Carethers JM, Farquhar MG. Ghosh P, et al. Mol Biol Cell. 2010 Jul 1;21(13):2338-54. doi: 10.1091/mbc.e10-01-0028. Epub 2010 May 12. Mol Biol Cell. 2010. PMID: 20462955 Free PMC article.

6

Expression of GIV/Girdin, a metastasis-related protein, predicts patient survival in colon cancer.

Garcia-Marcos M, Jung BH, Ear J, Cabrera B, Carethers JM, Ghosh P. Garcia-Marcos M, et al. FASEB J. 2011 Feb;25(2):590-9. doi: 10.1096/fj.10-167304. Epub 2010 Oct 25. FASEB J. 2011. PMID: 20974669 Free PMC article.

7

A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals.

Garcia-Marcos M, Ear J, Farquhar MG, Ghosh P. Garcia-Marcos M, et al. Mol Biol Cell. 2011 Mar 1;22(5):673-86. doi: 10.1091/mbc.E10-08-0738. Epub 2011 Jan 5. Mol Biol Cell. 2011. PMID: 21209316 Free PMC article.

8

Molecular basis of a novel oncogenic mutation in GNAO1.

Garcia-Marcos M, Ghosh P, Farquhar MG. Garcia-Marcos M, et al. Oncogene. 2011 Jun 9;30(23):2691-6. doi: 10.1038/onc.2010.645. Epub 2011 Feb 14. Oncogene. 2011. PMID: 21317923 Free PMC article.

9

GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression.

Ghosh P, Garcia-Marcos M, Farquhar MG. Ghosh P, et al. Cell Adh Migr. 2011 May-Jun;5(3):237-48. doi: 10.4161/cam.5.3.15909. Epub 2011 May 1. Cell Adh Migr. 2011. PMID: 21546796 Free PMC article.

10

G Protein binding sites on Calnuc (nucleobindin 1) and NUCB2 (nucleobindin 2) define a new class of G(alpha)i-regulatory motifs.

Garcia-Marcos M, Kietrsunthorn PS, Wang H, Ghosh P, Farquhar MG. Garcia-Marcos M, et al. J Biol Chem. 2011 Aug 12;286(32):28138-49. doi: 10.1074/jbc.M110.204099. Epub 2011 Jun 8. J Biol Chem. 2011. PMID: 21653697 Free PMC article.

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