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Page 1
Integrins in angiogenesis and lymphangiogenesis.
Avraamides CJ, Garmy-Susini B, Varner JA. Avraamides CJ, et al. Nat Rev Cancer. 2008 Aug;8(8):604-17. doi: 10.1038/nrc2353. Epub 2008 May 22. Nat Rev Cancer. 2008. PMID: 18497750 Free PMC article. Review.
Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.
Garmy-Susini B, Avraamides CJ, Schmid MC, Foubert P, Ellies LG, Barnes L, Feral C, Papayannopoulou T, Lowy A, Blair SL, Cheresh D, Ginsberg M, Varner JA. Garmy-Susini B, et al. Among authors: avraamides cj. Cancer Res. 2010 Apr 15;70(8):3042-51. doi: 10.1158/0008-5472.CAN-09-3761. Epub 2010 Apr 13. Cancer Res. 2010. PMID: 20388801 Free PMC article.
Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression.
Schmid MC, Avraamides CJ, Dippold HC, Franco I, Foubert P, Ellies LG, Acevedo LM, Manglicmot JR, Song X, Wrasidlo W, Blair SL, Ginsberg MH, Cheresh DA, Hirsch E, Field SJ, Varner JA. Schmid MC, et al. Among authors: avraamides cj. Cancer Cell. 2011 Jun 14;19(6):715-27. doi: 10.1016/j.ccr.2011.04.016. Cancer Cell. 2011. PMID: 21665146 Free PMC article.
PI3Kα activates integrin α4β1 to establish a metastatic niche in lymph nodes.
Garmy-Susini B, Avraamides CJ, Desgrosellier JS, Schmid MC, Foubert P, Ellies LG, Lowy AM, Blair SL, Vandenberg SR, Datnow B, Wang HY, Cheresh DA, Varner J. Garmy-Susini B, et al. Among authors: avraamides cj. Proc Natl Acad Sci U S A. 2013 May 28;110(22):9042-7. doi: 10.1073/pnas.1219603110. Epub 2013 May 13. Proc Natl Acad Sci U S A. 2013. PMID: 23671068 Free PMC article.
Hic-5 promotes endothelial cell migration to lysophosphatidic acid.
Avraamides C, Bromberg ME, Gaughan JP, Thomas SM, Tsygankov AY, Panetti TS. Avraamides C, et al. Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H193-203. doi: 10.1152/ajpheart.00728.2006. Epub 2007 Mar 2. Am J Physiol Heart Circ Physiol. 2007. PMID: 17337598 Free article.