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What makes a good drug target?
Gashaw I, Ellinghaus P, Sommer A, Asadullah K. Gashaw I, et al. Among authors: ellinghaus p. Drug Discov Today. 2011 Dec;16(23-24):1037-43. doi: 10.1016/j.drudis.2011.09.007. Epub 2011 Sep 16. Drug Discov Today. 2011. PMID: 21945861 Review.
What makes a good drug target?
Gashaw I, Ellinghaus P, Sommer A, Asadullah K. Gashaw I, et al. Among authors: ellinghaus p. Drug Discov Today. 2012 Feb;17 Suppl:S24-30. doi: 10.1016/j.drudis.2011.12.008. Epub 2011 Dec 11. Drug Discov Today. 2012. PMID: 22155646
BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I.
Ellinghaus P, Heisler I, Unterschemmann K, Haerter M, Beck H, Greschat S, Ehrmann A, Summer H, Flamme I, Oehme F, Thierauch K, Michels M, Hess-Stumpp H, Ziegelbauer K. Ellinghaus P, et al. Cancer Med. 2013 Oct;2(5):611-24. doi: 10.1002/cam4.112. Epub 2013 Aug 20. Cancer Med. 2013. PMID: 24403227 Free PMC article.
A role for coagulation factor Xa in experimental pulmonary arterial hypertension.
Delbeck M, Nickel KF, Perzborn E, Ellinghaus P, Strassburger J, Kast R, Laux V, Schäfer S, Schermuly RT, von Degenfeld G. Delbeck M, et al. Among authors: ellinghaus p. Cardiovasc Res. 2011 Oct 1;92(1):159-68. doi: 10.1093/cvr/cvr168. Epub 2011 Jun 15. Cardiovasc Res. 2011. PMID: 21676958
Rogaratinib: A potent and selective pan-FGFR inhibitor with broad antitumor activity in FGFR-overexpressing preclinical cancer models.
Grünewald S, Politz O, Bender S, Héroult M, Lustig K, Thuss U, Kneip C, Kopitz C, Zopf D, Collin MP, Boemer U, Ince S, Ellinghaus P, Mumberg D, Hess-Stumpp H, Ziegelbauer K. Grünewald S, et al. Among authors: ellinghaus p. Int J Cancer. 2019 Sep 1;145(5):1346-1357. doi: 10.1002/ijc.32224. Epub 2019 Mar 13. Int J Cancer. 2019. PMID: 30807645 Free PMC article.
45 results