Danthi SJ - Search Results

1

Prospective CCR5 small molecule antagonist compound design using a combined mutagenesis/modeling approach.

Metz M, Bourque E, Labrecque J, Danthi SJ, Langille J, Harwig C, Yang W, Darkes MC, Lau G, Santucci Z, Bridger GJ, Schols D, Fricker SP, Skerlj RT. Metz M, et al. Among authors: danthi sj. J Am Chem Soc. 2011 Oct 19;133(41):16477-85. doi: 10.1021/ja2043722. Epub 2011 Sep 23. J Am Chem Soc. 2011. PMID: 21942640

2

Mitigating hERG Inhibition: Design of Orally Bioavailable CCR5 Antagonists as Potent Inhibitors of R5 HIV-1 Replication.

Skerlj R, Bridger G, Zhou Y, Bourque E, McEachern E, Danthi S, Langille J, Harwig C, Veale D, Carpenter B, Ba T, Bey M, Baird I, Wilson T, Metz M, MacFarland R, Mosi R, Bodart V, Wong R, Fricker S, Huskens D, Schols D. Skerlj R, et al. ACS Med Chem Lett. 2012 Jan 25;3(3):216-21. doi: 10.1021/ml2002604. eCollection 2012 Mar 8. ACS Med Chem Lett. 2012. PMID: 24900457 Free PMC article.

3

Identification and Characterization of Inhibitors of a Neutral Amino Acid Transporter, SLC6A19, Using Two Functional Cell-Based Assays.

Danthi SJ, Liang B, Smicker O, Coupland B, Gregory J, Gefteas E, Tietz D, Klodnitsky H, Randall K, Belanger A, Kuntzweiler TA. Danthi SJ, et al. SLAS Discov. 2019 Feb;24(2):111-120. doi: 10.1177/2472555218794627. Epub 2018 Dec 27. SLAS Discov. 2019. PMID: 30589598 Free article.

4

Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines.

Martyn DC, Nijjar A, Celatka CA, Mazitschek R, Cortese JF, Tyndall E, Liu H, Fitzgerald MM, O'Shea TJ, Danthi S, Clardy J. Martyn DC, et al. Bioorg Med Chem Lett. 2010 Jan 1;20(1):228-31. doi: 10.1016/j.bmcl.2009.10.133. Epub 2009 Oct 31. Bioorg Med Chem Lett. 2010. PMID: 19914064

5

Alfuzosin delays cardiac repolarization by a novel mechanism.

Lacerda AE, Kuryshev YA, Chen Y, Renganathan M, Eng H, Danthi SJ, Kramer JW, Yang T, Brown AM. Lacerda AE, et al. Among authors: danthi sj. J Pharmacol Exp Ther. 2008 Feb;324(2):427-33. doi: 10.1124/jpet.107.128405. Epub 2007 Nov 6. J Pharmacol Exp Ther. 2008. PMID: 17986649

6

Curcumin potently blocks Kv1.4 potassium channels.

Liu H, Danthi SJ, Enyeart JJ. Liu H, et al. Among authors: danthi sj. Biochem Biophys Res Commun. 2006 Jun 16;344(4):1161-5. doi: 10.1016/j.bbrc.2006.04.020. Biochem Biophys Res Commun. 2006. PMID: 16647042 Free PMC article.

7

Angiotensin II inhibits bTREK-1 K+ channels in adrenocortical cells by separate Ca2+- and ATP hydrolysis-dependent mechanisms.

Enyeart JJ, Danthi SJ, Liu H, Enyeart JA. Enyeart JJ, et al. Among authors: danthi sj. J Biol Chem. 2005 Sep 2;280(35):30814-28. doi: 10.1074/jbc.M504283200. Epub 2005 Jul 1. J Biol Chem. 2005. PMID: 15994319 Free article.

8

Modulation of native T-type calcium channels by omega-3 fatty acids.

Danthi SJ, Enyeart JA, Enyeart JJ. Danthi SJ, et al. Biochem Biophys Res Commun. 2005 Feb 11;327(2):485-93. doi: 10.1016/j.bbrc.2004.12.033. Biochem Biophys Res Commun. 2005. PMID: 15629140

9

TREK-1 K+ channels couple angiotensin II receptors to membrane depolarization and aldosterone secretion in bovine adrenal glomerulosa cells.

Enyeart JA, Danthi SJ, Enyeart JJ. Enyeart JA, et al. Among authors: danthi sj. Am J Physiol Endocrinol Metab. 2004 Dec;287(6):E1154-65. doi: 10.1152/ajpendo.00223.2004. Epub 2004 Aug 17. Am J Physiol Endocrinol Metab. 2004. PMID: 15315905 Free article.

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