Frey PA - Search Results

1

Radical stabilization is crucial in the mechanism of action of lysine 5,6-aminomutase: role of tyrosine-263α as revealed by electron paramagnetic resonance spectroscopy.

Chen YH, Maity AN, Pan YC, Frey PA, Ke SC. Chen YH, et al. Among authors: frey pa. J Am Chem Soc. 2011 Nov 2;133(43):17152-5. doi: 10.1021/ja207766c. Epub 2011 Oct 12. J Am Chem Soc. 2011. PMID: 21939264

2

Evidence for conformational movement and radical mechanism in the reaction of 4-thia-L-lysine with lysine 5,6-aminomutase.

Maity AN, Hsieh CP, Huang MH, Chen YH, Tang KH, Behshad E, Frey PA, Ke SC. Maity AN, et al. Among authors: frey pa. J Phys Chem B. 2009 Sep 10;113(36):12161-3. doi: 10.1021/jp905357a. J Phys Chem B. 2009. PMID: 19685884

3

Mechanism-based inhibition reveals transitions between two conformational states in the action of lysine 5,6-aminomutase: a combination of electron paramagnetic resonance spectroscopy, electron nuclear double resonance spectroscopy, and density functional theory study.

Chen YH, Maity AN, Frey PA, Ke SC. Chen YH, et al. Among authors: frey pa. J Am Chem Soc. 2013 Jan 16;135(2):788-94. doi: 10.1021/ja309603a. Epub 2012 Dec 27. J Am Chem Soc. 2013. PMID: 23231091

4

Coordination and mechanism of reversible cleavage of S-adenosylmethionine by the [4Fe-4S] center in lysine 2,3-aminomutase.

Chen D, Walsby C, Hoffman BM, Frey PA. Chen D, et al. Among authors: frey pa. J Am Chem Soc. 2003 Oct 1;125(39):11788-9. doi: 10.1021/ja036120z. J Am Chem Soc. 2003. PMID: 14505379

5

How an enzyme tames reactive intermediates: positioning of the active-site components of lysine 2,3-aminomutase during enzymatic turnover as determined by ENDOR spectroscopy.

Lees NS, Chen D, Walsby CJ, Behshad E, Frey PA, Hoffman BM. Lees NS, et al. Among authors: frey pa. J Am Chem Soc. 2006 Aug 9;128(31):10145-54. doi: 10.1021/ja061282r. J Am Chem Soc. 2006. PMID: 16881644

6

A locking mechanism preventing radical damage in the absence of substrate, as revealed by the x-ray structure of lysine 5,6-aminomutase.

Berkovitch F, Behshad E, Tang KH, Enns EA, Frey PA, Drennan CL. Berkovitch F, et al. Among authors: frey pa. Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15870-5. doi: 10.1073/pnas.0407074101. Epub 2004 Oct 28. Proc Natl Acad Sci U S A. 2004. PMID: 15514022 Free PMC article.

7

Radical triplets and suicide inhibition in reactions of 4-thia-D- and 4-thia-L-lysine with lysine 5,6-aminomutase.

Tang KH, Mansoorabadi SO, Reed GH, Frey PA. Tang KH, et al. Among authors: frey pa. Biochemistry. 2009 Sep 1;48(34):8151-60. doi: 10.1021/bi900828f. Biochemistry. 2009. PMID: 19634897 Free PMC article.

8

An organic radical in the lysine 2,3-aminomutase reaction.

Ballinger MD, Reed GH, Frey PA. Ballinger MD, et al. Among authors: frey pa. Biochemistry. 1992 Feb 4;31(4):949-53. doi: 10.1021/bi00119a001. Biochemistry. 1992. PMID: 1310425

9

Pulsed electron paramagnetic resonance studies of the lysine 2,3-aminomutase substrate radical: evidence for participation of pyridoxal 5'-phosphate in a radical rearrangement.

Ballinger MD, Frey PA, Reed GH, LoBrutto R. Ballinger MD, et al. Among authors: frey pa. Biochemistry. 1995 Aug 8;34(31):10086-93. doi: 10.1021/bi00031a033. Biochemistry. 1995. PMID: 7632680

10

Kinetic and biochemical analysis of the mechanism of action of lysine 5,6-aminomutase.

Tang KH, Casarez AD, Wu W, Frey PA. Tang KH, et al. Among authors: frey pa. Arch Biochem Biophys. 2003 Oct 1;418(1):49-54. doi: 10.1016/s0003-9861(03)00346-1. Arch Biochem Biophys. 2003. PMID: 13679082

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