Savall BM - Search Results

1

Tricyclic aminopyrimidine histamine H4 receptor antagonists.

Savall BM, Gomez L, Chavez F, Curtis M, Meduna SP, Kearney A, Dunford P, Cowden J, Thurmond RL, Grice C, Edwards JP. Savall BM, et al. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6577-81. doi: 10.1016/j.bmcl.2011.08.014. Epub 2011 Aug 19. Bioorg Med Chem Lett. 2011. PMID: 21920744

2

Clinical Development of Histamine H₄ Receptor Antagonists.

Thurmond RL, Venable J, Savall B, La D, Snook S, Dunford PJ, Edwards JP. Thurmond RL, et al. Handb Exp Pharmacol. 2017;241:301-320. doi: 10.1007/164_2016_130. Handb Exp Pharmacol. 2017. PMID: 28233185 Review.

3

Agonist/antagonist modulation in a series of 2-aryl benzimidazole H4 receptor ligands.

Savall BM, Edwards JP, Venable JD, Buzard DJ, Thurmond R, Hack M, McGovern P. Savall BM, et al. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3367-71. doi: 10.1016/j.bmcl.2010.04.017. Epub 2010 Apr 11. Bioorg Med Chem Lett. 2010. PMID: 20452213

4

Triamino pyrimidines and pyridines as histamine H(4) receptor modulators.

Meduna SP, Savall BM, Cai H, Edwards JP, Thurmond RL, McGovern PM. Meduna SP, et al. Among authors: savall bm. Bioorg Med Chem Lett. 2011 May 15;21(10):3113-6. doi: 10.1016/j.bmcl.2011.03.017. Epub 2011 Mar 30. Bioorg Med Chem Lett. 2011. PMID: 21458260

5

Discovery and SAR of 6-alkyl-2,4-diaminopyrimidines as histamine H₄ receptor antagonists.

Savall BM, Chavez F, Tays K, Dunford PJ, Cowden JM, Hack MD, Wolin RL, Thurmond RL, Edwards JP. Savall BM, et al. J Med Chem. 2014 Mar 27;57(6):2429-39. doi: 10.1021/jm401727m. Epub 2014 Feb 21. J Med Chem. 2014. PMID: 24495018

6

The effect of pK(a) on pyrimidine/pyridine-derived histamine H4 ligands.

Savall BM, Meduna SP, Venable J, Wei J, Smith RC, Hack MD, Thurmond RL, McGovern P, Edwards JP. Savall BM, et al. Bioorg Med Chem Lett. 2014 Dec 1;24(23):5489-92. doi: 10.1016/j.bmcl.2014.10.013. Epub 2014 Oct 13. Bioorg Med Chem Lett. 2014. PMID: 25455490

7

Diaminopyrimidines, diaminopyridines and diaminopyridazines as histamine H4 receptor modulators.

Savall BM, Meduna SP, Tays K, Cai H, Thurmond RL, McGovern P, Gaul M, Zhao BP, Edwards JP. Savall BM, et al. Bioorg Med Chem Lett. 2015 Feb 15;25(4):956-9. doi: 10.1016/j.bmcl.2014.12.027. Epub 2014 Dec 23. Bioorg Med Chem Lett. 2015. PMID: 25595684

8

Functional Profiling of 2-Aminopyrimidine Histamine H4 Receptor Modulators.

Tichenor MS, Thurmond RL, Venable JD, Savall BM. Tichenor MS, et al. Among authors: savall bm. J Med Chem. 2015 Sep 24;58(18):7119-27. doi: 10.1021/acs.jmedchem.5b00516. Epub 2015 Jun 3. J Med Chem. 2015. PMID: 25993395 Review.

9

Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase.

Eccles W, Blevitt JM, Booker JN, Chrovian CC, Crawford S, de Leon AR, Deng X, Fourie AM, Grice CA, Herman K, Karlsson L, Kearney AM, Lee-Dutra A, Liang J, Luna R, Pippel D, Rao N, Riley JP, Santillán A, Savall B, Tanis VM, Xue X, Young AL. Eccles W, et al. Bioorg Med Chem Lett. 2013 Feb 1;23(3):811-5. doi: 10.1016/j.bmcl.2012.11.074. Epub 2012 Dec 5. Bioorg Med Chem Lett. 2013. PMID: 23260350

10

Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.

Grice CA, Tays KL, Savall BM, Wei J, Butler CR, Axe FU, Bembenek SD, Fourie AM, Dunford PJ, Lundeen K, Coles F, Xue X, Riley JP, Williams KN, Karlsson L, Edwards JP. Grice CA, et al. Among authors: savall bm. J Med Chem. 2008 Jul 24;51(14):4150-69. doi: 10.1021/jm701575k. Epub 2008 Jun 28. J Med Chem. 2008. PMID: 18588282

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