Kuca K - Search Results

1

Synthesis and in vitro evaluation of 7-methoxy-N-(pent-4-enyl)-1,2,3,4-tetrahydroacridin-9-amine-new tacrine derivate with cholinergic properties.

Korabecny J, Musilek K, Zemek F, Horova A, Holas O, Nepovimova E, Opletalova V, Hroudova J, Fisar Z, Jung YS, Kuca K. Korabecny J, et al. Among authors: kuca k. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6563-6. doi: 10.1016/j.bmcl.2011.08.042. Epub 2011 Aug 22. Bioorg Med Chem Lett. 2011. PMID: 21920739

2

Synthesis of a new reactivator of tabun-inhibited acetylcholinesterase.

Kuca K, Bielavský J, Cabal J, Kassa J. Kuca K, et al. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3545-7. doi: 10.1016/s0960-894x(03)00751-0. Bioorg Med Chem Lett. 2003. PMID: 14505667

3

Design and synthesis of new bis-pyridinium oxime reactivators for acetylcholinesterase inhibited by organophosphorous nerve agents.

Kim TH, Kuca K, Jun D, Jung YS. Kim TH, et al. Among authors: kuca k. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2914-7. doi: 10.1016/j.bmcl.2005.03.060. Epub 2005 Apr 21. Bioorg Med Chem Lett. 2005. PMID: 15911280

4

Effective bisquaternary reactivators of tabun-inhibited AChE.

Kuca K, Cabal J, Musilek K, Jun D, Bajgar J. Kuca K, et al. J Appl Toxicol. 2005 Nov-Dec;25(6):491-5. doi: 10.1002/jat.1084. J Appl Toxicol. 2005. PMID: 16092078

5

Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.

Musilek K, Kuca K, Jun D, Dohnal V, Dolezal M. Musilek K, et al. Among authors: kuca k. Bioorg Med Chem Lett. 2006 Feb;16(3):622-7. doi: 10.1016/j.bmcl.2005.10.059. Epub 2005 Nov 8. Bioorg Med Chem Lett. 2006. PMID: 16288867

6

Synthesis of a novel series of bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.

Musilek K, Kuca K, Jun D, Dohnal V, Dolezal M. Musilek K, et al. Among authors: kuca k. J Enzyme Inhib Med Chem. 2005 Oct;20(5):409-15. doi: 10.1080/14756360500179762. J Enzyme Inhib Med Chem. 2005. PMID: 16335048 Free article.

7

Structural requirements of acetylcholinesterase reactivators.

Kuca K, Juna D, Musilek K. Kuca K, et al. Mini Rev Med Chem. 2006 Mar;6(3):269-77. doi: 10.2174/138955706776073510. Mini Rev Med Chem. 2006. PMID: 16515465 Review.

8

Russian VX: inhibition and reactivation of acetylcholinesterase compared with VX agent.

Kuca K, Jun D, Cabal J, Hrabinova M, Bartosova L, Opletalova V. Kuca K, et al. Basic Clin Pharmacol Toxicol. 2006 Apr;98(4):389-94. doi: 10.1111/j.1742-7843.2006.pto_267.x. Basic Clin Pharmacol Toxicol. 2006. PMID: 16623863 Free article.

9

Bis-pyridiumaldoxime reactivators connected with CH2O(CH2)n OCH2 linkers between pyridinium rings and their reactivity against VX.

Oh KA, Yang GY, Jun D, Kuca K, Jung YS. Oh KA, et al. Among authors: kuca k. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4852-5. doi: 10.1016/j.bmcl.2006.06.063. Epub 2006 Jul 7. Bioorg Med Chem Lett. 2006. PMID: 16828550

10

[Synthesis of reactivators of phosphorylated acetylcholinesterase of bis-pyridiniumdialdoxime type with a 3-oxapentane connecting chain and their testing in vitro on a model of the enzyme inhibited by chlorpyrifos and methylchlorpyrifos].

Musílek K, Kuca K, Jun D, Dohnal V, Kim TH, Jung YS, Dolezal M. Musílek K, et al. Among authors: kuca k. Ceska Slov Farm. 2006 May;55(3):115-9. Ceska Slov Farm. 2006. PMID: 16838488 Czech.

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