Horova A - Search Results

1

Synthesis and in vitro evaluation of 7-methoxy-N-(pent-4-enyl)-1,2,3,4-tetrahydroacridin-9-amine-new tacrine derivate with cholinergic properties.

Korabecny J, Musilek K, Zemek F, Horova A, Holas O, Nepovimova E, Opletalova V, Hroudova J, Fisar Z, Jung YS, Kuca K. Korabecny J, et al. Among authors: horova a. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6563-6. doi: 10.1016/j.bmcl.2011.08.042. Epub 2011 Aug 22. Bioorg Med Chem Lett. 2011. PMID: 21920739

2

Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1,3-diyl linkage-Preparation, in vitro screening and molecular docking.

Musilek K, Komloova M, Holas O, Horova A, Pohanka M, Gunn-Moore F, Dohnal V, Dolezal M, Kuca K. Musilek K, et al. Among authors: horova a. Bioorg Med Chem. 2011 Jan 15;19(2):754-62. doi: 10.1016/j.bmc.2010.12.021. Epub 2010 Dec 16. Bioorg Med Chem. 2011. PMID: 21215642

3

Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment.

Komloova M, Musilek K, Horova A, Holas O, Dohnal V, Gunn-Moore F, Kuca K. Komloova M, et al. Among authors: horova a. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2505-9. doi: 10.1016/j.bmcl.2011.02.047. Epub 2011 Feb 21. Bioorg Med Chem Lett. 2011. PMID: 21397501

4

Preparation, in vitro evaluation and molecular modelling of pyridinium-quinolinium/isoquinolinium non-symmetrical bisquaternary cholinesterase inhibitors.

Komloova M, Horova A, Hrabinova M, Jun D, Dolezal M, Vinsova J, Kuca K, Musilek K. Komloova M, et al. Among authors: horova a. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6663-6. doi: 10.1016/j.bmcl.2013.10.043. Epub 2013 Oct 31. Bioorg Med Chem Lett. 2013. PMID: 24220173

5

7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies.

Korabecny J, Dolezal R, Cabelova P, Horova A, Hruba E, Ricny J, Sedlacek L, Nepovimova E, Spilovska K, Andrs M, Musilek K, Opletalova V, Sepsova V, Ripova D, Kuca K. Korabecny J, et al. Among authors: horova a. Eur J Med Chem. 2014 Jul 23;82:426-38. doi: 10.1016/j.ejmech.2014.05.066. Epub 2014 May 27. Eur J Med Chem. 2014. PMID: 24929293

6

Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity.

Nepovimova E, Korabecny J, Dolezal R, Babkova K, Ondrejicek A, Jun D, Sepsova V, Horova A, Hrabinova M, Soukup O, Bukum N, Jost P, Muckova L, Kassa J, Malinak D, Andrs M, Kuca K. Nepovimova E, et al. Among authors: horova a. J Med Chem. 2015 Nov 25;58(22):8985-9003. doi: 10.1021/acs.jmedchem.5b01325. Epub 2015 Nov 10. J Med Chem. 2015. PMID: 26503905

7

7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies.

Spilovska K, Korabecny J, Kral J, Horova A, Musilek K, Soukup O, Drtinova L, Gazova Z, Siposova K, Kuca K. Spilovska K, et al. Among authors: horova a. Molecules. 2013 Feb 20;18(2):2397-418. doi: 10.3390/molecules18022397. Molecules. 2013. PMID: 23429378 Free PMC article.

8

Preparation, in vitro screening and molecular modelling of monoquaternary compounds related to the selective acetylcholinesterase inhibitor BW284c51.

Benek O, Musilek K, Horova A, Dohnal V, Dolezal R, Kuca K. Benek O, et al. Among authors: horova a. Med Chem. 2014;11(1):21-9. doi: 10.2174/1573406410666140428153110. Med Chem. 2014. PMID: 24773345

9

7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment.

Korabecny J, Andrs M, Nepovimova E, Dolezal R, Babkova K, Horova A, Malinak D, Mezeiova E, Gorecki L, Sepsova V, Hrabinova M, Soukup O, Jun D, Kuca K. Korabecny J, et al. Among authors: horova a. Molecules. 2015 Dec 10;20(12):22084-101. doi: 10.3390/molecules201219836. Molecules. 2015. PMID: 26690394 Free PMC article.

10

Development of small bisquaternary cholinesterase inhibitors as drugs for pre-treatment of nerve agent poisonings.

Kuca K, Karasova JZ, Soukup O, Kassa J, Novotna E, Sepsova V, Horova A, Pejchal J, Hrabinova M, Vodakova E, Jun D, Nepovimova E, Valis M, Musilek K. Kuca K, et al. Among authors: horova a. Drug Des Devel Ther. 2018 Mar 9;12:505-512. doi: 10.2147/DDDT.S133038. eCollection 2018. Drug Des Devel Ther. 2018. PMID: 29563775 Free PMC article.

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