Akilesh S - Search Results

1

Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis.

Akilesh S, Suleiman H, Yu H, Stander MC, Lavin P, Gbadegesin R, Antignac C, Pollak M, Kopp JB, Winn MP, Shaw AS. Akilesh S, et al. J Clin Invest. 2011 Oct;121(10):4127-37. doi: 10.1172/JCI46458. Epub 2011 Sep 12. J Clin Invest. 2011. PMID: 21911940 Free PMC article.

2

Rac1 activation in podocytes induces rapid foot process effacement and proteinuria.

Yu H, Suleiman H, Kim AH, Miner JH, Dani A, Shaw AS, Akilesh S. Yu H, et al. Among authors: akilesh s. Mol Cell Biol. 2013 Dec;33(23):4755-64. doi: 10.1128/MCB.00730-13. Epub 2013 Sep 23. Mol Cell Biol. 2013. PMID: 24061480 Free PMC article.

3

Podocytes use FcRn to clear IgG from the glomerular basement membrane.

Akilesh S, Huber TB, Wu H, Wang G, Hartleben B, Kopp JB, Miner JH, Roopenian DC, Unanue ER, Shaw AS. Akilesh S, et al. Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):967-72. doi: 10.1073/pnas.0711515105. Epub 2008 Jan 15. Proc Natl Acad Sci U S A. 2008. PMID: 18198272 Free PMC article.

4

Basic science meets clinical medicine: identification of a CD2AP-deficient patient.

Akilesh S, Koziell A, Shaw AS. Akilesh S, et al. Kidney Int. 2007 Nov;72(10):1181-3. doi: 10.1038/sj.ki.5002575. Kidney Int. 2007. PMID: 17972907 Free article.

5

Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism.

Akilesh S, Christianson GJ, Roopenian DC, Shaw AS. Akilesh S, et al. J Immunol. 2007 Oct 1;179(7):4580-8. doi: 10.4049/jimmunol.179.7.4580. J Immunol. 2007. PMID: 17878355

6

B cell-derived IL-4 acts on podocytes to induce proteinuria and foot process effacement.

Kim AH, Chung JJ, Akilesh S, Koziell A, Jain S, Hodgin JB, Miller MJ, Stappenbeck TS, Miner JH, Shaw AS. Kim AH, et al. Among authors: akilesh s. JCI Insight. 2017 Nov 2;2(21):e81836. doi: 10.1172/jci.insight.81836. JCI Insight. 2017. PMID: 29093269 Free PMC article.

7

Upregulated PD-1 signaling antagonizes glomerular health in aged kidneys and disease.

Pippin JW, Kaverina N, Wang Y, Eng DG, Zeng Y, Tran U, Loretz CJ, Chang A, Akilesh S, Poudel C, Perry HS, O'Connor C, Vaughan JC, Bitzer M, Wessely O, Shankland SJ. Pippin JW, et al. Among authors: akilesh s. J Clin Invest. 2022 Aug 15;132(16):e156250. doi: 10.1172/JCI156250. J Clin Invest. 2022. PMID: 35968783 Free PMC article.

8

Expression profiles of podocytes exposed to high glucose reveal new insights into early diabetic glomerulopathy.

Jain S, De Petris L, Hoshi M, Akilesh S, Chatterjee R, Liapis H. Jain S, et al. Among authors: akilesh s. Lab Invest. 2011 Apr;91(4):488-98. doi: 10.1038/labinvest.2010.188. Epub 2010 Nov 22. Lab Invest. 2011. PMID: 21102505 Free PMC article.

9

Monoclonal antibodies directed against human FcRn and their applications.

Christianson GJ, Sun VZ, Akilesh S, Pesavento E, Proetzel G, Roopenian DC. Christianson GJ, et al. Among authors: akilesh s. MAbs. 2012 Mar-Apr;4(2):208-16. doi: 10.4161/mabs.4.2.19397. Epub 2012 Mar 1. MAbs. 2012. PMID: 22453095 Free PMC article.

10

Global transcriptomic changes occur in aged mouse podocytes.

Wang Y, Eng DG, Kaverina NV, Loretz CJ, Koirala A, Akilesh S, Pippin JW, Shankland SJ. Wang Y, et al. Among authors: akilesh s. Kidney Int. 2020 Nov;98(5):1160-1173. doi: 10.1016/j.kint.2020.05.052. Epub 2020 Jun 25. Kidney Int. 2020. PMID: 32592814 Free PMC article.

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