Pearson RB - Search Results

1

AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy.

Astle MV, Hannan KM, Ng PY, Lee RS, George AJ, Hsu AK, Haupt Y, Hannan RD, Pearson RB. Astle MV, et al. Among authors: pearson rb. Oncogene. 2012 Apr 12;31(15):1949-62. doi: 10.1038/onc.2011.394. Epub 2011 Sep 12. Oncogene. 2012. PMID: 21909130 Free PMC article.

2

Ro 31-6045, the inactive analogue of the protein kinase C inhibitor Ro 31-8220, blocks in vivo activation of p70(s6k)/p85(s6k): implications for the analysis of S6K signalling.

Marmy-Conus N, Hannan KM, Pearson RB. Marmy-Conus N, et al. Among authors: pearson rb. FEBS Lett. 2002 May 22;519(1-3):135-40. doi: 10.1016/s0014-5793(02)02738-2. FEBS Lett. 2002. PMID: 12023032 Free article.

3

Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase.

Conus NM, Hannan KM, Cristiano BE, Hemmings BA, Pearson RB. Conus NM, et al. Among authors: pearson rb. J Biol Chem. 2002 Oct 11;277(41):38021-8. doi: 10.1074/jbc.M203387200. Epub 2002 Jul 30. J Biol Chem. 2002. PMID: 12149249 Free article.

4

Activation of S6K1 (p70 ribosomal protein S6 kinase 1) requires an initial calcium-dependent priming event involving formation of a high-molecular-mass signalling complex.

Hannan KM, Thomas G, Pearson RB. Hannan KM, et al. Among authors: pearson rb. Biochem J. 2003 Mar 1;370(Pt 2):469-77. doi: 10.1042/BJ20021709. Biochem J. 2003. PMID: 12429015 Free PMC article.

5

Protein kinase-dependent phosphorylation of the Menkes copper P-type ATPase.

Voskoboinik I, Fernando R, Veldhuis N, Hannan KM, Marmy-Conus N, Pearson RB, Camakaris J. Voskoboinik I, et al. Among authors: pearson rb. Biochem Biophys Res Commun. 2003 Mar 28;303(1):337-42. doi: 10.1016/s0006-291x(03)00329-2. Biochem Biophys Res Commun. 2003. PMID: 12646208

6

mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.

Hannan KM, Brandenburger Y, Jenkins A, Sharkey K, Cavanaugh A, Rothblum L, Moss T, Poortinga G, McArthur GA, Pearson RB, Hannan RD. Hannan KM, et al. Among authors: pearson rb. Mol Cell Biol. 2003 Dec;23(23):8862-77. doi: 10.1128/MCB.23.23.8862-8877.2003. Mol Cell Biol. 2003. PMID: 14612424 Free PMC article.

7

MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation.

Poortinga G, Hannan KM, Snelling H, Walkley CR, Jenkins A, Sharkey K, Wall M, Brandenburger Y, Palatsides M, Pearson RB, McArthur GA, Hannan RD. Poortinga G, et al. Among authors: pearson rb. EMBO J. 2004 Aug 18;23(16):3325-35. doi: 10.1038/sj.emboj.7600335. Epub 2004 Jul 29. EMBO J. 2004. PMID: 15282543 Free PMC article.

8

The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.

Ooms LM, Fedele CG, Astle MV, Ivetac I, Cheung V, Pearson RB, Layton MJ, Forrai A, Nandurkar HH, Mitchell CA. Ooms LM, et al. Among authors: pearson rb. Mol Biol Cell. 2006 Feb;17(2):607-22. doi: 10.1091/mbc.e05-05-0469. Epub 2005 Nov 9. Mol Biol Cell. 2006. PMID: 16280363 Free PMC article.

9

A specific role for AKT3 in the genesis of ovarian cancer through modulation of G(2)-M phase transition.

Cristiano BE, Chan JC, Hannan KM, Lundie NA, Marmy-Conus NJ, Campbell IG, Phillips WA, Robbie M, Hannan RD, Pearson RB. Cristiano BE, et al. Among authors: pearson rb. Cancer Res. 2006 Dec 15;66(24):11718-25. doi: 10.1158/0008-5472.CAN-06-1968. Cancer Res. 2006. PMID: 17178867

10

Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function.

Jastrzebski K, Hannan KM, Tchoubrieva EB, Hannan RD, Pearson RB. Jastrzebski K, et al. Among authors: pearson rb. Growth Factors. 2007 Aug;25(4):209-26. doi: 10.1080/08977190701779101. Growth Factors. 2007. PMID: 18092230 Review.

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