Lee RS - Search Results

1

AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy.

Astle MV, Hannan KM, Ng PY, Lee RS, George AJ, Hsu AK, Haupt Y, Hannan RD, Pearson RB. Astle MV, et al. Among authors: lee rs. Oncogene. 2012 Apr 12;31(15):1949-62. doi: 10.1038/onc.2011.394. Epub 2011 Sep 12. Oncogene. 2012. PMID: 21909130 Free PMC article.

2

AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer.

Chan JC, Hannan KM, Riddell K, Ng PY, Peck A, Lee RS, Hung S, Astle MV, Bywater M, Wall M, Poortinga G, Jastrzebski K, Sheppard KE, Hemmings BA, Hall MN, Johnstone RW, McArthur GA, Hannan RD, Pearson RB. Chan JC, et al. Among authors: lee rs. Sci Signal. 2011 Aug 30;4(188):ra56. doi: 10.1126/scisignal.2001754. Sci Signal. 2011. PMID: 21878679

3

Relative Expression Levels Rather Than Specific Activity Plays the Major Role in Determining In Vivo AKT Isoform Substrate Specificity.

Lee RS, House CM, Cristiano BE, Hannan RD, Pearson RB, Hannan KM. Lee RS, et al. Enzyme Res. 2011;2011:720985. doi: 10.4061/2011/720985. Epub 2011 Aug 22. Enzyme Res. 2011. PMID: 21869924 Free PMC article.

4

Cell cycle and growth stimuli regulate different steps of RNA polymerase I transcription.

Hung SS, Lesmana A, Peck A, Lee R, Tchoubrieva E, Hannan KM, Lin J, Sheppard KE, Jastrzebski K, Quinn LM, Rothblum LI, Pearson RB, Hannan RD, Sanij E. Hung SS, et al. Gene. 2017 May 15;612:36-48. doi: 10.1016/j.gene.2016.12.015. Epub 2016 Dec 15. Gene. 2017. PMID: 27989772

5

Myeloid progenitor cells lacking p53 exhibit delayed up-regulation of Puma and prolonged survival after cytokine deprivation.

Jabbour AM, Daunt CP, Green BD, Vogel S, Gordon L, Lee RS, Silke N, Pearson RB, Vandenberg CJ, Kelly PN, Nutt SL, Strasser A, Borner C, Ekert PG. Jabbour AM, et al. Among authors: lee rs. Blood. 2010 Jan 14;115(2):344-52. doi: 10.1182/blood-2009-07-230730. Epub 2009 Nov 17. Blood. 2010. PMID: 19965665 Free PMC article.

6

Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation.

Ma X, Zhang L, Song J, Nguyen E, Lee RS, Rodgers SJ, Li F, Huang C, Schittenhelm RB, Chan H, Chheang C, Wu J, Brown KK, Mitchell CA, Simpson KJ, Daly RJ. Ma X, et al. Among authors: lee rs. Nat Commun. 2019 Jan 17;10(1):296. doi: 10.1038/s41467-018-08154-1. Nat Commun. 2019. PMID: 30655532 Free PMC article.

7

Impact of the Anticancer Drug NT157 on Tyrosine Kinase Signaling Networks.

Su SP, Flashner-Abramson E, Klein S, Gal M, Lee RS, Wu J, Levitzki A, Daly RJ. Su SP, et al. Among authors: lee rs. Mol Cancer Ther. 2018 May;17(5):931-942. doi: 10.1158/1535-7163.MCT-17-0377. Epub 2018 Feb 12. Mol Cancer Ther. 2018. PMID: 29440449

8

FGFR3 signaling and function in triple negative breast cancer.

Chew NJ, Nguyen EV, Su SP, Novy K, Chan HC, Nguyen LK, Luu J, Simpson KJ, Lee RS, Daly RJ. Chew NJ, et al. Among authors: lee rs. Cell Commun Signal. 2020 Jan 27;18(1):13. doi: 10.1186/s12964-019-0486-4. Cell Commun Signal. 2020. PMID: 31987043 Free PMC article.

9

Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target.

Lee RS, Zhang L, Berger A, Lawrence MG, Song J, Niranjan B, Davies RG, Lister NL, Sandhu SK, Rubin MA, Risbridger GP, Taylor RA, Rickman DS, Horvath LG, Daly RJ. Lee RS, et al. Neoplasia. 2019 Apr;21(4):389-400. doi: 10.1016/j.neo.2019.02.005. Epub 2019 Mar 20. Neoplasia. 2019. PMID: 30901730 Free PMC article.

10

Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases.

Liu L, Phua YW, Lee RS, Ma X, Jenkins Y, Novy K, Humphrey ES, Chan H, Shearer R, Ong PC, Dai W, Saunders DN, Lucet IS, Daly RJ. Liu L, et al. Among authors: lee rs. J Biol Chem. 2016 Oct 7;291(41):21571-21583. doi: 10.1074/jbc.M116.748897. Epub 2016 Aug 16. J Biol Chem. 2016. PMID: 27531744 Free PMC article.

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