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The drug vehicle and solvent N-methylpyrrolidone is an immunomodulator and antimyeloma compound.
Shortt J, Hsu AK, Martin BP, Doggett K, Matthews GM, Doyle MA, Ellul J, Jockel TE, Andrews DM, Hogg SJ, Reitsma A, Faulkner D, Bergsagel PL, Chesi M, Heath JK, Denny WA, Thompson PE, Neeson PJ, Ritchie DS, McArthur GA, Johnstone RW. Shortt J, et al. Among authors: hsu ak. Cell Rep. 2014 May 22;7(4):1009-19. doi: 10.1016/j.celrep.2014.04.008. Epub 2014 May 9. Cell Rep. 2014. PMID: 24813887 Free article.
Early thymus and activation-regulated chemokine (TARC) reduction and response following panobinostat treatment in patients with relapsed/refractory Hodgkin lymphoma following autologous stem cell transplant.
Harrison SJ, Hsu AK, Neeson P, Younes A, Sureda A, Engert A, Prince HM, Li M, Savage P, Bugarini R, Williams D, Squier M, Ritchie DS. Harrison SJ, et al. Among authors: hsu ak. Leuk Lymphoma. 2014 May;55(5):1053-60. doi: 10.3109/10428194.2013.820287. Epub 2013 Aug 5. Leuk Lymphoma. 2014. PMID: 23822537
Myeloma natural killer cells are exhausted and have impaired regulation of activation.
D'Souza C, Keam SP, Yeang HXA, Neeson M, Richardson K, Hsu AK, Canfield R, Bezman N, Robbins M, Quach H, Ritchie DS, Harrison SJ, Trapani JA, Prince HM, Beavis PA, Darcy PK, Neeson PJ. D'Souza C, et al. Among authors: hsu ak. Haematologica. 2021 Sep 1;106(9):2522-2526. doi: 10.3324/haematol.2020.277525. Haematologica. 2021. PMID: 34011135 Free PMC article. No abstract available.
Induction of potent NK cell-dependent anti-myeloma cytotoxic T cells in response to combined mapatumumab and bortezomib.
Neeson PJ, Hsu AK, Chen YR, Halse HM, Loh J, Cordy R, Fielding K, Davis J, Noske J, Davenport AJ, Lindqvist-Gigg CA, Humphreys R, Tai T, Prince HM, Trapani JA, Smyth MJ, Ritchie DS. Neeson PJ, et al. Among authors: hsu ak. Oncoimmunology. 2015 May 27;4(9):e1038011. doi: 10.1080/2162402X.2015.1038011. eCollection 2015 Sep. Oncoimmunology. 2015. PMID: 26405606 Free PMC article.
68 results