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ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation.
Yang JY, Zong CS, Xia W, Yamaguchi H, Ding Q, Xie X, Lang JY, Lai CC, Chang CJ, Huang WC, Huang H, Kuo HP, Lee DF, Li LY, Lien HC, Cheng X, Chang KJ, Hsiao CD, Tsai FJ, Tsai CH, Sahin AA, Muller WJ, Mills GB, Yu D, Hortobagyi GN, Hung MC. Yang JY, et al. Among authors: lang jy. Nat Cell Biol. 2008 Feb;10(2):138-48. doi: 10.1038/ncb1676. Epub 2008 Jan 20. Nat Cell Biol. 2008. PMID: 18204439 Free PMC article.
The crosstalk of mTOR/S6K1 and Hedgehog pathways.
Wang Y, Ding Q, Yen CJ, Xia W, Izzo JG, Lang JY, Li CW, Hsu JL, Miller SA, Wang X, Lee DF, Hsu JM, Huo L, Labaff AM, Liu D, Huang TH, Lai CC, Tsai FJ, Chang WC, Chen CH, Wu TT, Buttar NS, Wang KK, Wu Y, Wang H, Ajani J, Hung MC. Wang Y, et al. Among authors: lang jy. Cancer Cell. 2012 Mar 20;21(3):374-87. doi: 10.1016/j.ccr.2011.12.028. Cancer Cell. 2012. PMID: 22439934 Free PMC article.
Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers.
Huang TH, Huo L, Wang YN, Xia W, Wei Y, Chang SS, Chang WC, Fang YF, Chen CT, Lang JY, Tu C, Wang Y, Hsu MC, Kuo HP, Ko HW, Shen J, Lee HH, Lee PC, Wu Y, Chen CH, Hung MC. Huang TH, et al. Among authors: lang jy. Cancer Cell. 2013 Jun 10;23(6):796-810. doi: 10.1016/j.ccr.2013.04.027. Cancer Cell. 2013. PMID: 23764002 Free PMC article.
APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis.
Ding Q, Chang CJ, Xie X, Xia W, Yang JY, Wang SC, Wang Y, Xia J, Chen L, Cai C, Li H, Yen CJ, Kuo HP, Lee DF, Lang J, Huo L, Cheng X, Chen YJ, Li CW, Jeng LB, Hsu JL, Li LY, Tan A, Curley SA, Ellis LM, Dubois RN, Hung MC. Ding Q, et al. Among authors: lang j. J Clin Invest. 2011 Nov;121(11):4526-36. doi: 10.1172/JCI45008. Epub 2011 Oct 10. J Clin Invest. 2011. PMID: 21985787 Free PMC article.
72 results