Olah T - Search Results

1

Full-scan high resolution accurate mass spectrometry (HRMS) in regulated bioanalysis: LC-HRMS for the quantitation of prednisone and prednisolone in human plasma.

Fung EN, Xia YQ, Aubry AF, Zeng J, Olah T, Jemal M. Fung EN, et al. Among authors: olah t. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Oct 1;879(27):2919-27. doi: 10.1016/j.jchromb.2011.08.025. Epub 2011 Aug 26. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21907643

2

A strategy for liquid chromatography/tandem mass spectrometry based quantitation of pegylated protein drugs in plasma using plasma protein precipitation with water-miscible organic solvents and subsequent trypsin digestion to generate surrogate peptides for detection.

Wu ST, Ouyang Z, Olah TV, Jemal M. Wu ST, et al. Among authors: olah tv. Rapid Commun Mass Spectrom. 2011 Jan 30;25(2):281-90. doi: 10.1002/rcm.4856. Rapid Commun Mass Spectrom. 2011. PMID: 21192023

3

Targeted quantitative bioanalysis in plasma using liquid chromatography/high-resolution accurate mass spectrometry: an evaluation of global selectivity as a function of mass resolving power and extraction window, with comparison of centroid and profile modes.

Xia YQ, Lau J, Olah T, Jemal M. Xia YQ, et al. Among authors: olah t. Rapid Commun Mass Spectrom. 2011 Oct 15;25(19):2863-78. doi: 10.1002/rcm.5178. Rapid Commun Mass Spectrom. 2011. PMID: 21913265

4

LC-MS/MS method using unbonded silica column and aqueous/methanol mobile phase for the simultaneous quantification of a drug candidate and co-administered metformin in rat plasma.

Discenza L, D'Arienzo C, Olah T, Jemal M. Discenza L, et al. Among authors: olah t. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Jun 1;878(19):1583-9. doi: 10.1016/j.jchromb.2010.04.018. Epub 2010 Apr 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2010. PMID: 20451474

5

It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS.

Ramanathan R, Jemal M, Ramagiri S, Xia YQ, Humpreys WG, Olah T, Korfmacher WA. Ramanathan R, et al. Among authors: olah t. J Mass Spectrom. 2011 Jun;46(6):595-601. doi: 10.1002/jms.1921. J Mass Spectrom. 2011. PMID: 21630388

6

Effect of mobile phase pH, aqueous-organic ratio, and buffer concentration on electrospray ionization tandem mass spectrometric fragmentation patterns: implications in liquid chromatography/tandem mass spectrometric bioanalysis.

Wang J, Aubry A, Bolgar MS, Gu H, Olah TV, Arnold M, Jemal M. Wang J, et al. Rapid Commun Mass Spectrom. 2010 Nov 30;24(22):3221-9. doi: 10.1002/rcm.4748. Rapid Commun Mass Spectrom. 2010. PMID: 20972995

7

The integration of ligand binding and LC-MS-based assays into bioanalytical strategies for protein analysis.

Zhang YJ, Olah TV, Zeng J. Zhang YJ, et al. Bioanalysis. 2014;6(13):1827-41. doi: 10.4155/bio.14.128. Bioanalysis. 2014. PMID: 25157488 Review.

8

Antibody-drug conjugate bioanalysis using LB-LC-MS/MS hybrid assays: strategies, methodology and correlation to ligand-binding assays.

Wang J, Gu H, Liu A, Kozhich A, Rangan V, Myler H, Luo L, Wong R, Sun H, Wang B, Vezina HE, Deshpande S, Zhang Y, Yang Z, Olah TV, Aubry AF, Arnold ME, Pillutla R, DeSilva B. Wang J, et al. Bioanalysis. 2016 Jul;8(13):1383-401. doi: 10.4155/bio-2016-0017. Epub 2016 Jun 9. Bioanalysis. 2016. PMID: 27277879

9

Pellet digestion: a simple and efficient sample preparation technique for LC-MS/MS quantification of large therapeutic proteins in plasma.

Ouyang Z, Furlong MT, Wu S, Sleczka B, Tamura J, Wang H, Suchard S, Suri A, Olah T, Tymiak A, Jemal M. Ouyang Z, et al. Among authors: olah t. Bioanalysis. 2012 Jan;4(1):17-28. doi: 10.4155/bio.11.286. Bioanalysis. 2012. PMID: 22191591

10

A universal surrogate peptide to enable LC-MS/MS bioanalysis of a diversity of human monoclonal antibody and human Fc-fusion protein drug candidates in pre-clinical animal studies.

Furlong MT, Ouyang Z, Wu S, Tamura J, Olah T, Tymiak A, Jemal M. Furlong MT, et al. Among authors: olah t. Biomed Chromatogr. 2012 Aug;26(8):1024-32. doi: 10.1002/bmc.2759. Epub 2012 May 24. Biomed Chromatogr. 2012. PMID: 22623136

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