Bon RS - Search Results

1

Development of highly potent inhibitors of the Ras-targeting human acyl protein thioesterases based on substrate similarity design.

Hedberg C, Dekker FJ, Rusch M, Renner S, Wetzel S, Vartak N, Gerding-Reimers C, Bon RS, Bastiaens PI, Waldmann H. Hedberg C, et al. Among authors: bon rs. Angew Chem Int Ed Engl. 2011 Oct 10;50(42):9832-7. doi: 10.1002/anie.201102965. Epub 2011 Sep 9. Angew Chem Int Ed Engl. 2011. PMID: 21905185

2

Development of selective RabGGTase inhibitors and crystal structure of a RabGGTase-inhibitor complex.

Guo Z, Wu YW, Tan KT, Bon RS, Guiu-Rozas E, Delon C, Nguyen TU, Wetzel S, Arndt S, Goody RS, Blankenfeldt W, Alexandrov K, Waldmann H. Guo Z, et al. Among authors: bon rs. Angew Chem Int Ed Engl. 2008;47(20):3747-50. doi: 10.1002/anie.200705795. Angew Chem Int Ed Engl. 2008. PMID: 18399557 No abstract available.

3

Structure-guided development of selective RabGGTase inhibitors.

Bon RS, Guo Z, Stigter EA, Wetzel S, Menninger S, Wolf A, Choidas A, Alexandrov K, Blankenfeldt W, Goody RS, Waldmann H. Bon RS, et al. Angew Chem Int Ed Engl. 2011 May 16;50(21):4957-61. doi: 10.1002/anie.201101210. Epub 2011 Apr 21. Angew Chem Int Ed Engl. 2011. PMID: 21520375 No abstract available.

4

Biology-oriented synthesis.

Wetzel S, Bon RS, Kumar K, Waldmann H. Wetzel S, et al. Among authors: bon rs. Angew Chem Int Ed Engl. 2011 Nov 11;50(46):10800-26. doi: 10.1002/anie.201007004. Epub 2011 Oct 28. Angew Chem Int Ed Engl. 2011. PMID: 22038946 Review.

5

Design, synthesis, and characterization of peptide-based rab geranylgeranyl transferase inhibitors.

Tan KT, Guiu-Rozas E, Bon RS, Guo Z, Delon C, Wetzel S, Arndt S, Alexandrov K, Waldmann H, Goody RS, Wu YW, Blankenfeldt W. Tan KT, et al. Among authors: bon rs. J Med Chem. 2009 Dec 24;52(24):8025-37. doi: 10.1021/jm901117d. J Med Chem. 2009. PMID: 19894725

6

Bioactivity-guided navigation of chemical space.

Bon RS, Waldmann H. Bon RS, et al. Acc Chem Res. 2010 Aug 17;43(8):1103-14. doi: 10.1021/ar100014h. Acc Chem Res. 2010. PMID: 20481515

7

Psoromic acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase.

Deraeve C, Guo Z, Bon RS, Blankenfeldt W, DiLucrezia R, Wolf A, Menninger S, Stigter EA, Wetzel S, Choidas A, Alexandrov K, Waldmann H, Goody RS, Wu YW. Deraeve C, et al. Among authors: bon rs. J Am Chem Soc. 2012 May 2;134(17):7384-91. doi: 10.1021/ja211305j. Epub 2012 Apr 22. J Am Chem Soc. 2012. PMID: 22480322

8

Development of selective, potent RabGGTase inhibitors.

Stigter EA, Guo Z, Bon RS, Wu YW, Choidas A, Wolf A, Menninger S, Waldmann H, Blankenfeldt W, Goody RS. Stigter EA, et al. Among authors: bon rs. J Med Chem. 2012 Oct 11;55(19):8330-40. doi: 10.1021/jm300624s. Epub 2012 Oct 3. J Med Chem. 2012. PMID: 22963166

9

Psoromic acid derivatives: a new family of small-molecule pre-mRNA splicing inhibitors discovered by a stage-specific high-throughput in vitro splicing assay.

Samatov TR, Wolf A, Odenwälder P, Bessonov S, Deraeve C, Bon RS, Waldmann H, Lührmann R. Samatov TR, et al. Among authors: bon rs. Chembiochem. 2012 Mar 19;13(5):640-4. doi: 10.1002/cbic.201100790. Epub 2012 Feb 14. Chembiochem. 2012. PMID: 22334518 No abstract available.

10

Analysis of the eukaryotic prenylome by isoprenoid affinity tagging.

Nguyen UT, Guo Z, Delon C, Wu Y, Deraeve C, Fränzel B, Bon RS, Blankenfeldt W, Goody RS, Waldmann H, Wolters D, Alexandrov K. Nguyen UT, et al. Among authors: bon rs. Nat Chem Biol. 2009 Apr;5(4):227-35. doi: 10.1038/nchembio.149. Epub 2009 Feb 15. Nat Chem Biol. 2009. PMID: 19219049

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