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KRN5500, a spicamycin derivative, exerts anti-myeloma effects through impairing both myeloma cells and osteoclasts.
Miki H, Ozaki S, Nakamura S, Oda A, Amou H, Ikegame A, Watanabe K, Hiasa M, Cui Q, Harada T, Fujii S, Nakano A, Kagawa K, Takeuchi K, Yata K, Sakai A, Abe M, Matsumoto T. Miki H, et al. Among authors: takeuchi k. Br J Haematol. 2011 Nov;155(3):328-39. doi: 10.1111/j.1365-2141.2011.08844.x. Epub 2011 Sep 9. Br J Haematol. 2011. PMID: 21902681 Free article.
Valproic acid exerts anti-tumor as well as anti-angiogenic effects on myeloma.
Kitazoe KI, Abe M, Hiasa M, Oda A, Amou H, Harada T, Nakano A, Takeuchi K, Hashimoto T, Ozaki S, Matsumoto T. Kitazoe KI, et al. Among authors: takeuchi k. Int J Hematol. 2009 Jan;89(1):45-57. doi: 10.1007/s12185-008-0226-9. Epub 2008 Dec 18. Int J Hematol. 2009. PMID: 19093163
Targeting myeloma-osteoclast interaction with Vγ9Vδ2 T cells.
Cui Q, Shibata H, Oda A, Amou H, Nakano A, Yata K, Hiasa M, Watanabe K, Nakamura S, Miki H, Harada T, Fujii S, Kagawa K, Takeuchi K, Ozaki S, Matsumoto T, Abe M. Cui Q, et al. Among authors: takeuchi k. Int J Hematol. 2011 Jul;94(1):63-70. doi: 10.1007/s12185-011-0885-9. Epub 2011 Jun 23. Int J Hematol. 2011. PMID: 21698356
Inhibition of TACE activity enhances the susceptibility of myeloma cells to TRAIL.
Kagawa K, Nakano A, Miki H, Oda A, Amou H, Takeuchi K, Nakamura S, Harada T, Fujii S, Yata K, Ozaki S, Matsumoto T, Abe M. Kagawa K, et al. Among authors: takeuchi k. PLoS One. 2012;7(2):e31594. doi: 10.1371/journal.pone.0031594. Epub 2012 Feb 28. PLoS One. 2012. PMID: 22389670 Free PMC article.
4,340 results