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KRN5500, a spicamycin derivative, exerts anti-myeloma effects through impairing both myeloma cells and osteoclasts.
Miki H, Ozaki S, Nakamura S, Oda A, Amou H, Ikegame A, Watanabe K, Hiasa M, Cui Q, Harada T, Fujii S, Nakano A, Kagawa K, Takeuchi K, Yata K, Sakai A, Abe M, Matsumoto T. Miki H, et al. Among authors: sakai a. Br J Haematol. 2011 Nov;155(3):328-39. doi: 10.1111/j.1365-2141.2011.08844.x. Epub 2011 Sep 9. Br J Haematol. 2011. PMID: 21902681 Free article.
Glycolysis inhibition inactivates ABC transporters to restore drug sensitivity in malignant cells.
Nakano A, Tsuji D, Miki H, Cui Q, El Sayed SM, Ikegame A, Oda A, Amou H, Nakamura S, Harada T, Fujii S, Kagawa K, Takeuchi K, Sakai A, Ozaki S, Okano K, Nakamura T, Itoh K, Matsumoto T, Abe M. Nakano A, et al. Among authors: sakai a. PLoS One. 2011;6(11):e27222. doi: 10.1371/journal.pone.0027222. Epub 2011 Nov 2. PLoS One. 2011. PMID: 22073292 Free PMC article.
Low-dose thalidomide plus low-dose dexamethasone therapy in patients with refractory multiple myeloma.
Murakami H, Handa H, Abe M, Iida S, Ishii A, Ishikawa T, Ishida T, Oota M, Ozaki S, Kosaka M, Sakai A, Sawamura M, Shimazaki C, Shimizu K, Takagi T, Hata H, Fukuhara T, Fujii H, Miyata A, Wakayama T, Takatsuki K. Murakami H, et al. Among authors: sakai a. Eur J Haematol. 2007 Sep;79(3):234-9. doi: 10.1111/j.1600-0609.2007.00908.x. Epub 2007 Jul 26. Eur J Haematol. 2007. PMID: 17655699 Clinical Trial.
A possible role for the loss of CD27-CD70 interaction in myelomagenesis.
Katayama Y, Sakai A, Oue N, Asaoku H, Otsuki T, Shiomomura T, Masuda R, Hino N, Takimoto Y, Imanaka F, Yasui W, Kimura A. Katayama Y, et al. Among authors: sakai a. Br J Haematol. 2003 Jan;120(2):223-34. doi: 10.1046/j.1365-2141.2003.04069.x. Br J Haematol. 2003. PMID: 12542479 Free article.
1,946 results