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Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice.
Bashashati M, Storr MA, Nikas SP, Wood JT, Godlewski G, Liu J, Ho W, Keenan CM, Zhang H, Alapafuja SO, Cravatt BF, Lutz B, Mackie K, Kunos G, Patel KD, Makriyannis A, Davison JS, Sharkey KA. Bashashati M, et al. Among authors: godlewski g. Br J Pharmacol. 2012 Mar;165(5):1556-71. doi: 10.1111/j.1476-5381.2011.01644.x. Br J Pharmacol. 2012. PMID: 21883147 Free PMC article.
Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity.
Gunduz-Cinar O, MacPherson KP, Cinar R, Gamble-George J, Sugden K, Williams B, Godlewski G, Ramikie TS, Gorka AX, Alapafuja SO, Nikas SP, Makriyannis A, Poulton R, Patel S, Hariri AR, Caspi A, Moffitt TE, Kunos G, Holmes A. Gunduz-Cinar O, et al. Among authors: godlewski g. Mol Psychiatry. 2013 Jul;18(7):813-23. doi: 10.1038/mp.2012.72. Epub 2012 Jun 12. Mol Psychiatry. 2013. PMID: 22688188 Free PMC article.
Endocannabinoids and the control of energy homeostasis.
Kunos G, Osei-Hyiaman D, Liu J, Godlewski G, Bátkai S. Kunos G, et al. Among authors: godlewski g. J Biol Chem. 2008 Nov 28;283(48):33021-5. doi: 10.1074/jbc.R800012200. Epub 2008 Aug 11. J Biol Chem. 2008. PMID: 18694938 Free PMC article. Review.
Coordinated action of a gut-liver pathway drives alcohol detoxification and consumption.
Fu Y, Mackowiak B, Lin YH, Maccioni L, Lehner T, Pan H, Guan Y, Godlewski G, Lu H, Chen C, Wei S, Feng D, Paloczi J, Zhou H, Pacher P, Zhang L, Kunos G, Gao B. Fu Y, et al. Among authors: godlewski g. Nat Metab. 2024 Jul;6(7):1380-1396. doi: 10.1038/s42255-024-01063-2. Epub 2024 Jun 20. Nat Metab. 2024. PMID: 38902331
Cannabinoformins: Designing Biguanide-Embedded, Orally Available, Peripherally Selective Cannabinoid-1 Receptor Antagonists for Metabolic Syndrome Disorders.
Dvorácskó S, Herrerias A, Oliverio A, Bhattacharjee P, Pommerolle L, Liu Z, Feng D, Lee YS, Hassan SA, Godlewski G, Cinar R, Iyer MR. Dvorácskó S, et al. Among authors: godlewski g. J Med Chem. 2023 Sep 14;66(17):11985-12004. doi: 10.1021/acs.jmedchem.3c00599. Epub 2023 Aug 23. J Med Chem. 2023. PMID: 37611316
Cannabinoid receptor type 1 (CB1R) inhibits hypothalamic leptin signaling via β-arrestin1 in complex with TC-PTP and STAT3.
Szanda G, Jourdan T, Wisniewski É, Cinar R, Godlewski G, Rajki A, Liu J, Chedester L, Szalai B, Tóth AD, Soltész-Katona E, Hunyady L, Inoue A, Horváth VB, Spät A, Tam J, Kunos G. Szanda G, et al. Among authors: godlewski g. iScience. 2023 Jun 25;26(7):107207. doi: 10.1016/j.isci.2023.107207. eCollection 2023 Jul 21. iScience. 2023. PMID: 37534180 Free PMC article.
Functional Selectivity of a Biased Cannabinoid-1 Receptor (CB1R) Antagonist.
Liu Z, Iyer MR, Godlewski G, Jourdan T, Liu J, Coffey NJ, Zawatsky CN, Puhl HL, Wess J, Meister J, Liow JS, Innis RB, Hassan SA, Lee YS, Kunos G, Cinar R. Liu Z, et al. Among authors: godlewski g. ACS Pharmacol Transl Sci. 2021 Apr 8;4(3):1175-1187. doi: 10.1021/acsptsci.1c00048. eCollection 2021 Jun 11. ACS Pharmacol Transl Sci. 2021. PMID: 34151207 Free PMC article.
196 results