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Page 1
Silencing of microRNA-21 in vivo ameliorates autoimmune splenomegaly in lupus mice.
Garchow BG, Bartulos Encinas O, Leung YT, Tsao PY, Eisenberg RA, Caricchio R, Obad S, Petri A, Kauppinen S, Kiriakidou M. Garchow BG, et al. Among authors: obad s. EMBO Mol Med. 2011 Oct;3(10):605-15. doi: 10.1002/emmm.201100171. Epub 2011 Sep 1. EMBO Mol Med. 2011. PMID: 21882343 Free PMC article.
LNA-mediated microRNA silencing in non-human primates.
Elmén J, Lindow M, Schütz S, Lawrence M, Petri A, Obad S, Lindholm M, Hedtjärn M, Hansen HF, Berger U, Gullans S, Kearney P, Sarnow P, Straarup EM, Kauppinen S. Elmén J, et al. Among authors: obad s. Nature. 2008 Apr 17;452(7189):896-9. doi: 10.1038/nature06783. Epub 2008 Mar 26. Nature. 2008. PMID: 18368051
Silencing of microRNA families by seed-targeting tiny LNAs.
Obad S, dos Santos CO, Petri A, Heidenblad M, Broom O, Ruse C, Fu C, Lindow M, Stenvang J, Straarup EM, Hansen HF, Koch T, Pappin D, Hannon GJ, Kauppinen S. Obad S, et al. Nat Genet. 2011 Mar 20;43(4):371-8. doi: 10.1038/ng.786. Nat Genet. 2011. PMID: 21423181 Free PMC article.
Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR.
Rottiers V, Obad S, Petri A, McGarrah R, Lindholm MW, Black JC, Sinha S, Goody RJ, Lawrence MS, deLemos AS, Hansen HF, Whittaker S, Henry S, Brookes R, Najafi-Shoushtari SH, Chung RT, Whetstine JR, Gerszten RE, Kauppinen S, Näär AM. Rottiers V, et al. Among authors: obad s. Sci Transl Med. 2013 Nov 20;5(212):212ra162. doi: 10.1126/scitranslmed.3006840. Sci Transl Med. 2013. PMID: 24259050 Free PMC article.
MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis.
Meisgen F, Xu N, Wei T, Janson PC, Obad S, Broom O, Nagy N, Kauppinen S, Kemény L, Ståhle M, Pivarcsi A, Sonkoly E. Meisgen F, et al. Among authors: obad s. Exp Dermatol. 2012 Apr;21(4):312-4. doi: 10.1111/j.1600-0625.2012.01462.x. Exp Dermatol. 2012. PMID: 22417311
LNA-mediated anti-miR-155 silencing in low-grade B-cell lymphomas.
Zhang Y, Roccaro AM, Rombaoa C, Flores L, Obad S, Fernandes SM, Sacco A, Liu Y, Ngo H, Quang P, Azab AK, Azab F, Maiso P, Reagan M, Brown JR, Thai TH, Kauppinen S, Ghobrial IM. Zhang Y, et al. Among authors: obad s. Blood. 2012 Aug 23;120(8):1678-86. doi: 10.1182/blood-2012-02-410647. Epub 2012 Jul 13. Blood. 2012. PMID: 22797699 Free article.
26 results