Ulu A - Search Results

1

Pharmacokinetics and in vivo potency of soluble epoxide hydrolase inhibitors in cynomolgus monkeys.

Ulu A, Appt S, Morisseau C, Hwang SH, Jones PD, Rose TE, Dong H, Lango J, Yang J, Tsai HJ, Miyabe C, Fortenbach C, Adams MR, Hammock BD. Ulu A, et al. Br J Pharmacol. 2012 Mar;165(5):1401-12. doi: 10.1111/j.1476-5381.2011.01641.x. Br J Pharmacol. 2012. PMID: 21880036 Free PMC article.

2

Soluble epoxide hydrolase inhibitors reduce the development of atherosclerosis in apolipoprotein e-knockout mouse model.

Ulu A, Davis BB, Tsai HJ, Kim IH, Morisseau C, Inceoglu B, Fiehn O, Hammock BD, Weiss RH. Ulu A, et al. J Cardiovasc Pharmacol. 2008 Oct;52(4):314-23. doi: 10.1097/FJC.0b013e318185fa3c. J Cardiovasc Pharmacol. 2008. PMID: 18791465 Free PMC article.

3

Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model.

Liu JY, Yang J, Inceoglu B, Qiu H, Ulu A, Hwang SH, Chiamvimonvat N, Hammock BD. Liu JY, et al. Among authors: ulu a. Biochem Pharmacol. 2010 Mar 15;79(6):880-7. doi: 10.1016/j.bcp.2009.10.025. Epub 2009 Nov 5. Biochem Pharmacol. 2010. PMID: 19896470 Free PMC article.

4

Analgesia mediated by soluble epoxide hydrolase inhibitors is dependent on cAMP.

Inceoglu B, Wagner K, Schebb NH, Morisseau C, Jinks SL, Ulu A, Hegedus C, Rose T, Brosnan R, Hammock BD. Inceoglu B, et al. Among authors: ulu a. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5093-7. doi: 10.1073/pnas.1101073108. Epub 2011 Mar 7. Proc Natl Acad Sci U S A. 2011. PMID: 21383170 Free PMC article.

5

Inhibition of soluble epoxide hydrolase contributes to the anti-inflammatory effect of antimicrobial triclocarban in a murine model.

Liu JY, Qiu H, Morisseau C, Hwang SH, Tsai HJ, Ulu A, Chiamvimonvat N, Hammock BD. Liu JY, et al. Among authors: ulu a. Toxicol Appl Pharmacol. 2011 Sep 1;255(2):200-6. doi: 10.1016/j.taap.2011.06.017. Epub 2011 Jun 25. Toxicol Appl Pharmacol. 2011. PMID: 21741984 Free PMC article.

6

Role of soluble epoxide hydrolase phosphatase activity in the metabolism of lysophosphatidic acids.

Morisseau C, Schebb NH, Dong H, Ulu A, Aronov PA, Hammock BD. Morisseau C, et al. Among authors: ulu a. Biochem Biophys Res Commun. 2012 Mar 23;419(4):796-800. doi: 10.1016/j.bbrc.2012.02.108. Epub 2012 Feb 24. Biochem Biophys Res Commun. 2012. PMID: 22387545 Free PMC article.

7

Use of a soluble epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis.

Guedes AG, Morisseau C, Sole A, Soares JH, Ulu A, Dong H, Hammock BD. Guedes AG, et al. Among authors: ulu a. Vet Anaesth Analg. 2013 Jul;40(4):440-8. doi: 10.1111/vaa.12030. Epub 2013 Mar 7. Vet Anaesth Analg. 2013. PMID: 23463912 Free PMC article.

8

Anti-inflammatory effects of ω-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II-dependent hypertension.

Ulu A, Harris TR, Morisseau C, Miyabe C, Inoue H, Schuster G, Dong H, Iosif AM, Liu JY, Weiss RH, Chiamvimonvat N, Imig JD, Hammock BD. Ulu A, et al. J Cardiovasc Pharmacol. 2013 Sep;62(3):285-97. doi: 10.1097/FJC.0b013e318298e460. J Cardiovasc Pharmacol. 2013. PMID: 23676336 Free PMC article.

9

An omega-3 epoxide of docosahexaenoic acid lowers blood pressure in angiotensin-II-dependent hypertension.

Ulu A, Stephen Lee KS, Miyabe C, Yang J, Hammock BG, Dong H, Hammock BD. Ulu A, et al. J Cardiovasc Pharmacol. 2014 Jul;64(1):87-99. doi: 10.1097/FJC.0000000000000094. J Cardiovasc Pharmacol. 2014. PMID: 24691274 Free PMC article.

10

Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy.

Lee KS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. Lee KS, et al. Among authors: ulu a. J Med Chem. 2014 Aug 28;57(16):7016-30. doi: 10.1021/jm500694p. Epub 2014 Aug 11. J Med Chem. 2014. PMID: 25079952 Free PMC article.

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