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A kinase interacting protein (AKIP1) is a key regulator of cardiac stress.
Sastri M, Haushalter KJ, Panneerselvam M, Chang P, Fridolfsson H, Finley JC, Ng D, Schilling JM, Miyanohara A, Day ME, Hakozaki H, Petrosyan S, Koller A, King CC, Darshi M, Blumenthal DK, Ali SS, Roth DM, Patel HH, Taylor SS. Sastri M, et al. Among authors: miyanohara a. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):E387-96. doi: 10.1073/pnas.1221670110. Epub 2013 Jan 14. Proc Natl Acad Sci U S A. 2013. PMID: 23319652 Free PMC article.
Increased smooth muscle cell expression of caveolin-1 and caveolae contribute to the pathophysiology of idiopathic pulmonary arterial hypertension.
Patel HH, Zhang S, Murray F, Suda RY, Head BP, Yokoyama U, Swaney JS, Niesman IR, Schermuly RT, Pullamsetti SS, Thistlethwaite PA, Miyanohara A, Farquhar MG, Yuan JX, Insel PA. Patel HH, et al. Among authors: miyanohara a. FASEB J. 2007 Sep;21(11):2970-9. doi: 10.1096/fj.07-8424com. Epub 2007 Apr 30. FASEB J. 2007. PMID: 17470567
Cardiac-specific overexpression of caveolin-3 induces endogenous cardiac protection by mimicking ischemic preconditioning.
Tsutsumi YM, Horikawa YT, Jennings MM, Kidd MW, Niesman IR, Yokoyama U, Head BP, Hagiwara Y, Ishikawa Y, Miyanohara A, Patel PM, Insel PA, Patel HH, Roth DM. Tsutsumi YM, et al. Among authors: miyanohara a. Circulation. 2008 Nov 4;118(19):1979-88. doi: 10.1161/CIRCULATIONAHA.108.788331. Epub 2008 Oct 20. Circulation. 2008. PMID: 18936328 Free PMC article.
Loss of caveolin-1 accelerates neurodegeneration and aging.
Head BP, Peart JN, Panneerselvam M, Yokoyama T, Pearn ML, Niesman IR, Bonds JA, Schilling JM, Miyanohara A, Headrick J, Ali SS, Roth DM, Patel PM, Patel HH. Head BP, et al. Among authors: miyanohara a. PLoS One. 2010 Dec 23;5(12):e15697. doi: 10.1371/journal.pone.0015697. PLoS One. 2010. PMID: 21203469 Free PMC article.
Mitochondria-localized caveolin in adaptation to cellular stress and injury.
Fridolfsson HN, Kawaraguchi Y, Ali SS, Panneerselvam M, Niesman IR, Finley JC, Kellerhals SE, Migita MY, Okada H, Moreno AL, Jennings M, Kidd MW, Bonds JA, Balijepalli RC, Ross RS, Patel PM, Miyanohara A, Chen Q, Lesnefsky EJ, Head BP, Roth DM, Insel PA, Patel HH. Fridolfsson HN, et al. Among authors: miyanohara a. FASEB J. 2012 Nov;26(11):4637-49. doi: 10.1096/fj.12-215798. Epub 2012 Aug 2. FASEB J. 2012. PMID: 22859372 Free PMC article.
Synapsin-caveolin-1 gene therapy preserves neuronal and synaptic morphology and prevents neurodegeneration in a mouse model of AD.
Wang S, Leem JS, Podvin S, Hook V, Kleschevnikov N, Savchenko P, Dhanani M, Zhou K, Kelly IC, Zhang T, Miyanohara A, Nguyen P, Kleschevnikov A, Wagner SL, Trojanowski JQ, Roth DM, Patel HH, Patel PM, Head BP. Wang S, et al. Among authors: miyanohara a. Mol Ther Methods Clin Dev. 2021 Mar 29;21:434-450. doi: 10.1016/j.omtm.2021.03.021. eCollection 2021 Jun 11. Mol Ther Methods Clin Dev. 2021. PMID: 33981778 Free PMC article.
Subpial delivery of adeno-associated virus 9-synapsin-caveolin-1 (AAV9-SynCav1) preserves motor neuron and neuromuscular junction morphology, motor function, delays disease onset, and extends survival in hSOD1G93A mice.
Wang S, Ichinomiya T, Savchenko P, Wang D, Sawada A, Li X, Duong T, Li W, Bonds JA, Kim EJ, Miyanohara A, Roth DM, Patel HH, Patel PM, Tadokoro T, Marsala M, Head BP. Wang S, et al. Among authors: miyanohara a. Theranostics. 2022 Jul 11;12(12):5389-5403. doi: 10.7150/thno.72614. eCollection 2022. Theranostics. 2022. PMID: 35910808 Free PMC article.
Intravenous adeno-associated virus serotype 8 encoding urocortin-2 provides sustained augmentation of left ventricular function in mice.
Gao MH, Lai NC, Miyanohara A, Schilling JM, Suarez J, Tang T, Guo T, Tang R, Parikh J, Giamouridis D, Dillmann WH, Patel HH, Roth DM, Dalton ND, Hammond HK. Gao MH, et al. Among authors: miyanohara a. Hum Gene Ther. 2013 Sep;24(9):777-85. doi: 10.1089/hum.2013.088. Hum Gene Ther. 2013. PMID: 23931341 Free PMC article.
74 results