Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

33 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Prokaryotic ABCF proteins in overcoming ribosomal stalling: mechanisms, evolution, and perspective for applications in Bio-manufacturing.
Takada H, Sugimoto R, Oshima T. Takada H, et al. Biosci Biotechnol Biochem. 2024 Dec 23:zbae201. doi: 10.1093/bbb/zbae201. Online ahead of print. Biosci Biotechnol Biochem. 2024. PMID: 39716376
ABCF proteins (ABCFs) are key components of prokaryotic translation systems, resolving ribosomal stalling. These ATPases contain two ATPase domains and interdomain linker, the length and composition of which are key determinants of their function. Antibiotic resistance ABC …
ABCF proteins (ABCFs) are key components of prokaryotic translation systems, resolving ribosomal stalling. These ATPases contain two …
Resolution of ribosomal stalling by EF-P and ABCF ATPases YfmR and YkpA/YbiT.
Takada H, Fujiwara K, Atkinson GC, Chiba S, Hauryliuk V. Takada H, et al. Nucleic Acids Res. 2024 Sep 9;52(16):9854-9866. doi: 10.1093/nar/gkae556. Nucleic Acids Res. 2024. PMID: 38943426 Free PMC article.
Members of the F subfamily of ABC ATPases (ABCFs) have been long hypothesised to promote translation of such problematic motifs. ...
Members of the F subfamily of ABC ATPases (ABCFs) have been long hypothesised to promote translation of such problematic motifs. ...
The ABCF proteins in Escherichia coli individually cope with 'hard-to-translate' nascent peptide sequences.
Chadani Y, Yamanouchi S, Uemura E, Yamasaki K, Niwa T, Ikeda T, Kurihara M, Iwasaki W, Taguchi H. Chadani Y, et al. Nucleic Acids Res. 2024 Jun 10;52(10):5825-5840. doi: 10.1093/nar/gkae309. Nucleic Acids Res. 2024. PMID: 38661232 Free PMC article.
The correspondence between noncanonical translations and ABCFs was YheS for the translational arrest by nascent SecM, YbiT for poly-basic sequence-dependent stalling and poly-acidic sequence-dependent intrinsic ribosome destabilization (IRD), EttA for IRD at the early stag …
The correspondence between noncanonical translations and ABCFs was YheS for the translational arrest by nascent SecM, YbiT for poly-b …
YfmR is a translation factor that prevents ribosome stalling and cell death in the absence of EF-P.
Hong HR, Prince CR, Tetreault DD, Wu L, Feaga HA. Hong HR, et al. Proc Natl Acad Sci U S A. 2024 Feb 20;121(8):e2314437121. doi: 10.1073/pnas.2314437121. Epub 2024 Feb 13. Proc Natl Acad Sci U S A. 2024. PMID: 38349882 Free PMC article.
YfmR is an ABCF ATPase that is closely related to both Uup and EttA, ABCFs that bind the ribosomal E-site and are conserved in more than 50% of bacterial genomes. ...
YfmR is an ABCF ATPase that is closely related to both Uup and EttA, ABCFs that bind the ribosomal E-site and are conserved in more t …
Identification and expression analysis of ATP-binding cassette (ABC) transporters revealed its role in regulating stress response in pear (Pyrus bretchneideri).
Kou X, Zhao Z, Xu X, Li C, Wu J, Zhang S. Kou X, et al. BMC Genomics. 2024 Feb 12;25(1):169. doi: 10.1186/s12864-024-10063-1. BMC Genomics. 2024. PMID: 38347517 Free PMC article.
RESULTS: In this study, 177 ABC transporter genes were successfully identified in the pear genome, classified into seven subfamilies: 8 ABCAs, 40 ABCBs, 24 ABCCs, 8 ABCDs, 9 ABCEs, 8 ABCFs, and 80 ABCGs. Ten motifs were common among all ABC transporter proteins, while dist …
RESULTS: In this study, 177 ABC transporter genes were successfully identified in the pear genome, classified into seven subfamilies: 8 ABCA …
Hierarchy and interconnected networks in the WhiB7 mediated transcriptional response to antibiotic stress in Mycobacterium abscessus.
Hurst-Hess K, McManaman C, Yang Y, Gupta S, Ghosh P. Hurst-Hess K, et al. PLoS Genet. 2023 Dec 6;19(12):e1011060. doi: 10.1371/journal.pgen.1011060. eCollection 2023 Dec. PLoS Genet. 2023. PMID: 38055757 Free PMC article.
Our results suggest that while some genes within the regulon (eg. erm41, hflX, eis2 and the ABCFs) play a major role in resistance, others make smaller contributions (eg. MAB_4324c and MAB_1409c) and the observed hypersensitivity deltaMabwhiB7 is a cumulative effect of the …
Our results suggest that while some genes within the regulon (eg. erm41, hflX, eis2 and the ABCFs) play a major role in resistance, o …
YfmR is a translation factor that prevents ribosome stalling and cell death in the absence of EF-P.
Hong HR, Prince CR, Tetreault DD, Wu L, Feaga HA. Hong HR, et al. bioRxiv [Preprint]. 2023 Dec 5:2023.08.04.552005. doi: 10.1101/2023.08.04.552005. bioRxiv. 2023. Update in: Proc Natl Acad Sci U S A. 2024 Feb 20;121(8):e2314437121. doi: 10.1073/pnas.2314437121 PMID: 37577462 Free PMC article. Updated. Preprint.
YfmR is an ABCF ATPase that is closely related to both Uup and EttA, ABCFs that bind the ribosomal E-site and are conserved in more than 50% of bacterial genomes. ...
YfmR is an ABCF ATPase that is closely related to both Uup and EttA, ABCFs that bind the ribosomal E-site and are conserved in more t …
Comparative genetic, biochemical, and biophysical analyses of the four E. coli ABCF paralogs support distinct functions related to mRNA translation.
Ousalem F, Singh S, Bailey NA, Wong KH, Zhu L, Neky MJ, Sibindi C, Fei J, Gonzalez RL, Boël G, Hunt JF. Ousalem F, et al. bioRxiv [Preprint]. 2023 Jun 12:2023.06.11.543863. doi: 10.1101/2023.06.11.543863. bioRxiv. 2023. PMID: 37398404 Free PMC article. Preprint.
We herein compare the four Escherichia coli K12 ABCFs - EttA, Uup, YbiT, and YheS - using assays previously employed to demonstrate EttA gates the first step of polypeptide elongation on the ribosome dependent on ATP/ADP ratio. ...
We herein compare the four Escherichia coli K12 ABCFs - EttA, Uup, YbiT, and YheS - using assays previously employed to demonstrate E …
Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria: VmlR2, Ard1 and CplR.
Obana N, Takada H, Crowe-McAuliffe C, Iwamoto M, Egorov AA, Wu KJY, Chiba S, Murina V, Paternoga H, Tresco BIC, Nomura N, Myers AG, Atkinson GC, Wilson DN, Hauryliuk V. Obana N, et al. Nucleic Acids Res. 2023 May 22;51(9):4536-4554. doi: 10.1093/nar/gkad193. Nucleic Acids Res. 2023. PMID: 36951104 Free PMC article.
Genome-encoded antibiotic resistance (ARE) ATP-binding cassette (ABC) proteins of the F subfamily (ARE-ABCFs) mediate intrinsic resistance in diverse Gram-positive bacteria. The diversity of chromosomally-encoded ARE-ABCFs is far from being fully experimentally expl …
Genome-encoded antibiotic resistance (ARE) ATP-binding cassette (ABC) proteins of the F subfamily (ARE-ABCFs) mediate intrinsic resis …
33 results