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The majority of animal genes are required for wild-type fitness.
Ramani AK, Chuluunbaatar T, Verster AJ, Na H, Vu V, Pelte N, Wannissorn N, Jiao A, Fraser AG. Ramani AK, et al. Among authors: wannissorn n. Cell. 2012 Feb 17;148(4):792-802. doi: 10.1016/j.cell.2012.01.019. Cell. 2012. PMID: 22341449 Free article.