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Page 1
Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control.
Pannekoek WJ, van Dijk JJ, Chan OY, Huveneers S, Linnemann JR, Spanjaard E, Brouwer PM, van der Meer AJ, Zwartkruis FJ, Rehmann H, de Rooij J, Bos JL. Pannekoek WJ, et al. Among authors: rehmann h. Cell Signal. 2011 Dec;23(12):2056-64. doi: 10.1016/j.cellsig.2011.07.022. Epub 2011 Aug 4. Cell Signal. 2011. PMID: 21840392
The RapGEF PDZ-GEF2 is required for maturation of cell-cell junctions.
Dubé N, Kooistra MR, Pannekoek WJ, Vliem MJ, Oorschot V, Klumperman J, Rehmann H, Bos JL. Dubé N, et al. Among authors: rehmann h. Cell Signal. 2008 Sep;20(9):1608-15. doi: 10.1016/j.cellsig.2008.05.006. Epub 2008 May 23. Cell Signal. 2008. PMID: 18585005
Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.
Gloerich M, Ponsioen B, Vliem MJ, Zhang Z, Zhao J, Kooistra MR, Price LS, Ritsma L, Zwartkruis FJ, Rehmann H, Jalink K, Bos JL. Gloerich M, et al. Among authors: rehmann h. Mol Cell Biol. 2010 Nov;30(22):5421-31. doi: 10.1128/MCB.00463-10. Epub 2010 Sep 20. Mol Cell Biol. 2010. PMID: 20855527 Free PMC article.
Communication between the regulatory and the catalytic region of the cAMP-responsive guanine nucleotide exchange factor Epac.
Rehmann H, Rueppel A, Bos JL, Wittinghofer A. Rehmann H, et al. J Biol Chem. 2003 Jun 27;278(26):23508-14. doi: 10.1074/jbc.M301680200. Epub 2003 Apr 21. J Biol Chem. 2003. PMID: 12707263 Free article.
Epac is inhibited by an intramolecular interaction between the cAMP-binding domain and the catalytic region in the absence of cAMP. cAMP binding is proposed to induce a conformational change, which allows a LID, an alpha-helix at the C-terminal end of the cAMP-binding site, to co …
Epac is inhibited by an intramolecular interaction between the cAMP-binding domain and the catalytic region in the absence of cAMP. cAMP bin …
AF6 negatively regulates Rap1-induced cell adhesion.
Zhang Z, Rehmann H, Price LS, Riedl J, Bos JL. Zhang Z, et al. Among authors: rehmann h. J Biol Chem. 2005 Sep 30;280(39):33200-5. doi: 10.1074/jbc.M505057200. Epub 2005 Jul 28. J Biol Chem. 2005. PMID: 16051602 Free article.
80 results