Han H - Search Results

1

DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter.

Han H, Cortez CC, Yang X, Nichols PW, Jones PA, Liang G. Han H, et al. Hum Mol Genet. 2011 Nov 15;20(22):4299-310. doi: 10.1093/hmg/ddr356. Epub 2011 Aug 11. Hum Mol Genet. 2011. PMID: 21835883 Free PMC article.

2

Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer.

Wolff EM, Byun HM, Han HF, Sharma S, Nichols PW, Siegmund KD, Yang AS, Jones PA, Liang G. Wolff EM, et al. PLoS Genet. 2010 Apr 22;6(4):e1000917. doi: 10.1371/journal.pgen.1000917. PLoS Genet. 2010. PMID: 20421991 Free PMC article.

3

Gene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions.

Yang X, Noushmehr H, Han H, Andreu-Vieyra C, Liang G, Jones PA. Yang X, et al. Among authors: han h. PLoS Genet. 2012;8(3):e1002604. doi: 10.1371/journal.pgen.1002604. Epub 2012 Mar 29. PLoS Genet. 2012. PMID: 22479200 Free PMC article.

4

Gene body methylation can alter gene expression and is a therapeutic target in cancer.

Yang X, Han H, De Carvalho DD, Lay FD, Jones PA, Liang G. Yang X, et al. Among authors: han h. Cancer Cell. 2014 Oct 13;26(4):577-90. doi: 10.1016/j.ccr.2014.07.028. Epub 2014 Sep 25. Cancer Cell. 2014. PMID: 25263941 Free PMC article.

5

Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells.

Sharma S, Gerke DS, Han HF, Jeong S, Stallcup MR, Jones PA, Liang G. Sharma S, et al. Epigenetics Chromatin. 2012 Jan 27;5(1):3. doi: 10.1186/1756-8935-5-3. Epigenetics Chromatin. 2012. PMID: 22284370 Free PMC article.

6

Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA.

Jeong S, Liang G, Sharma S, Lin JC, Choi SH, Han H, Yoo CB, Egger G, Yang AS, Jones PA. Jeong S, et al. Among authors: han h. Mol Cell Biol. 2009 Oct;29(19):5366-76. doi: 10.1128/MCB.00484-09. Epub 2009 Jul 20. Mol Cell Biol. 2009. PMID: 19620278 Free PMC article.

7

Targeting DNA methylation for epigenetic therapy.

Yang X, Lay F, Han H, Jones PA. Yang X, et al. Among authors: han h. Trends Pharmacol Sci. 2010 Nov;31(11):536-46. doi: 10.1016/j.tips.2010.08.001. Epub 2010 Sep 16. Trends Pharmacol Sci. 2010. PMID: 20846732 Free PMC article. Review.

8

Synergistic re-activation of epigenetically silenced genes by combinatorial inhibition of DNMTs and LSD1 in cancer cells.

Han H, Yang X, Pandiyan K, Liang G. Han H, et al. PLoS One. 2013 Sep 6;8(9):e75136. doi: 10.1371/journal.pone.0075136. eCollection 2013. PLoS One. 2013. PMID: 24040395 Free PMC article.

9

Epigenetic alterations in bladder cancer and their potential clinical implications.

Han H, Wolff EM, Liang G. Han H, et al. Adv Urol. 2012;2012:546917. doi: 10.1155/2012/546917. Epub 2012 Jun 21. Adv Urol. 2012. PMID: 22829811 Free PMC article.

10

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts.

Roulois D, Loo Yau H, Singhania R, Wang Y, Danesh A, Shen SY, Han H, Liang G, Jones PA, Pugh TJ, O'Brien C, De Carvalho DD. Roulois D, et al. Among authors: han h. Cell. 2015 Aug 27;162(5):961-73. doi: 10.1016/j.cell.2015.07.056. Cell. 2015. PMID: 26317465 Free PMC article.

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