De Clercq E - Search Results

1

Bis[3,5-bis(benzylidene)-4-oxo-1-piperidinyl]amides: a novel class of potent cytotoxins.

Das S, Das U, Varela-Ramírez A, Lema C, Aguilera RJ, Balzarini J, De Clercq E, Dimmock SG, Gorecki DK, Dimmock JR. Das S, et al. Among authors: de clercq e. ChemMedChem. 2011 Oct 4;6(10):1892-9. doi: 10.1002/cmdc.201100199. Epub 2011 Aug 8. ChemMedChem. 2011. PMID: 21826795 Free PMC article.

2

Cytotoxic 1,4-bis(2-oxo-1-cycloalkylmethylene)benzenes and related compounds.

Dimmock JR, Jha A, Kumar P, Zello GA, Quail JW, Oloo EO, Oucharek JJ, Pasha MK, Seitz D, Sharma RK, Allen TM, Santos CL, Manavathu EK, De Clercq E, Balzarini J, Stables JP. Dimmock JR, et al. Among authors: de clercq e. Eur J Med Chem. 2002 Jan;37(1):35-44. doi: 10.1016/s0223-5234(01)01294-6. Eur J Med Chem. 2002. PMID: 11841873

3

Correlations between cytotoxicity and topography of some 2-arylidenebenzocycloalkanones determined by X-ray crystallography.

Dimmock JR, Zello GA, Oloo EO, Quail JW, Kraatz HB, Perjési P, Aradi F, Takács-Novák K, Allen TM, Santos CL, Balzarini J, De Clercq E, Stables JP. Dimmock JR, et al. Among authors: de clercq e. J Med Chem. 2002 Jul 4;45(14):3103-11. doi: 10.1021/jm010559p. J Med Chem. 2002. PMID: 12086496

4

Alkyloxyphenyl furano pyrimidines as potent and selective anti-VZV agents with enhanced water solubility.

McGuigan C, Blewett S, Siccardi D, Erichsen JT, Andrei G, Snoek R, De Clercq E, Balzarini J. McGuigan C, et al. Among authors: de clercq e. Antivir Chem Chemother. 2002 Mar;13(2):91-9. doi: 10.1177/095632020201300203. Antivir Chem Chemother. 2002. PMID: 12238533 Free article.

5

Synthesis, conformational analysis and antiviral and antitumoral activity of new 1,2-disubstituted carbocyclic nucleosides.

Santana L, Teijeira M, Uriarte E, Balzarini J, De Clercq E. Santana L, et al. Among authors: de clercq e. Eur J Med Chem. 2002 Sep;37(9):755-60. doi: 10.1016/s0223-5234(02)01352-1. Eur J Med Chem. 2002. PMID: 12350292

6

Synthesis and biological activity of strongly fluorescent tricyclic analogues of acyclovir and ganciclovir.

Goslinski T, Golankiewicz B, De Clercq E, Balzarini J. Goslinski T, et al. Among authors: de clercq e. J Med Chem. 2002 Nov 7;45(23):5052-7. doi: 10.1021/jm020827z. J Med Chem. 2002. PMID: 12408716

7

Cytotoxic 1,3-diarylidene-2-tetralones and related compounds.

Dimmock JR, Padmanilyam MP, Zello GA, Quail JW, Oloo EO, Prisciak JS, Kraatz HB, Cherkasov A, Lee JS, Allen TM, Santos CL, Manavathu EK, De Clercq E, Balzarini J, Stables JP. Dimmock JR, et al. Among authors: de clercq e. Eur J Med Chem. 2002 Oct;37(10):813-24. doi: 10.1016/s0223-5234(02)01402-2. Eur J Med Chem. 2002. PMID: 12446039

8

A thymidine phosphorylase-stable analogue of BVDU with significant antiviral activity.

Guenther S, Balzarini J, De Clercq E, Nair V. Guenther S, et al. Among authors: de clercq e. J Med Chem. 2002 Dec 5;45(25):5426-9. doi: 10.1021/jm025569k. J Med Chem. 2002. PMID: 12459010

9

Synthesis of 3'- and 5'-nitrooxy pyrimidine nucleoside nitrate esters: "nitric oxide donor" agents for evaluation as anticancer and antiviral agents.

Naimi E, Zhou A, Khalili P, Wiebe LI, Balzarini J, De Clercq E, Knaus EE. Naimi E, et al. Among authors: de clercq e. J Med Chem. 2003 Mar 13;46(6):995-1004. doi: 10.1021/jm020299r. J Med Chem. 2003. PMID: 12620076

10

Cytotoxic analogues of 2,6-bis(arylidene)cyclohexanones.

Dimmock JR, Padmanilayam MP, Zello GA, Nienaber KH, Allen TM, Santos CL, De Clercq E, Balzarini J, Manavathu EK, Stables JP. Dimmock JR, et al. Among authors: de clercq e. Eur J Med Chem. 2003 Feb;38(2):169-77. doi: 10.1016/s0223-5234(02)01444-7. Eur J Med Chem. 2003. PMID: 12620661

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