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Glucagon-like peptide-1 increases heart rate by a direct action on the sinus node.
Lubberding AF, Veedfald S, Achter JS, Nissen SD, Soattin L, Sorrentino A, Vega ET, Linz B, Eggertsen CHE, Mulvey J, Toräng S, Larsen SA, Nissen A, Petersen LG, Bilir SE, Bentzen BH, Rosenkilde MM, Hartmann B, Lilleør TNB, Qazi S, Møller CH, Tfelt-Hansen J, Sattler SM, Jespersen T, Holst JJ, Lundby A. Lubberding AF, et al. Among authors: bentzen bh. Cardiovasc Res. 2024 Oct 14;120(12):1427-1441. doi: 10.1093/cvr/cvae120. Cardiovasc Res. 2024. PMID: 38832935 Free PMC article.
A phase 1 trial of AP30663, a KCa2 channel inhibitor in development for conversion of atrial fibrillation.
Yfanti C, Vestbjerg B, Van't Westende J, Edvardsson N, Monfort LM, Olesen MS, Bentzen BH, Grunnet M, Eveleens Maarse BC, Diness JG, Kemme MJB, Sørensen U, Moerland M, van Esdonk MJ, Klaassen ES, Gal P, Holst AG. Yfanti C, et al. Among authors: bentzen bh. Br J Clin Pharmacol. 2024 Apr;90(4):1027-1035. doi: 10.1111/bcp.15973. Epub 2024 Jan 8. Br J Clin Pharmacol. 2024. PMID: 37990600 Clinical Trial.
Post-infection treatment with the E protein inhibitor BIT225 reduces disease severity and increases survival of K18-hACE2 transgenic mice infected with a lethal dose of SARS-CoV-2.
Ewart G, Bobardt M, Bentzen BH, Yan Y, Thomson A, Klumpp K, Becker S, Rosenkilde MM, Miller M, Gallay P. Ewart G, et al. Among authors: bentzen bh. PLoS Pathog. 2023 Aug 7;19(8):e1011328. doi: 10.1371/journal.ppat.1011328. eCollection 2023 Aug. PLoS Pathog. 2023. PMID: 37549173 Free PMC article.
Pharmacological inhibition of SK-channels with AP14145 prevents atrial arrhythmogenic changes in a porcine model for obstructive respiratory events.
Linz B, Hesselkilde EM, Skarsfeldt MA, Hertel JN, Sattler SM, Yan Y, Tfelt-Hansen J, Diness JG, Bentzen BH, Linz D, Jespersen T. Linz B, et al. Among authors: bentzen bh. J Cardiovasc Electrophysiol. 2023 Jan;34(1):126-134. doi: 10.1111/jce.15769. Epub 2022 Dec 20. J Cardiovasc Electrophysiol. 2023. PMID: 36482155 Free PMC article.
Reply to: How Many SARS-CoV-2 "Viroporins" Are Really Ion Channels?
Toft-Bertelsen TL, Jeppesen MG, Landbrug A, Mujezinovic A, Bentzen BH, Kledal TN, Rosenkilde MM. Toft-Bertelsen TL, et al. Among authors: bentzen bh. Commun Biol. 2022 Aug 25;5(1):860. doi: 10.1038/s42003-022-03670-9. Commun Biol. 2022. PMID: 36008476 Free PMC article. No abstract available.
81 results