Naturally acquired hemozoin by monocytes promotes suppression of RANTES in children with malarial anemia through an IL-10-dependent mechanism.
Were T, Davenport GC, Yamo EO, Hittner JB, Awandare GA, Otieno MF, Ouma C, Orago AS, Vulule JM, Ong'echa JM, Perkins DJ.
Were T, et al.
Microbes Infect. 2009 Jul-Aug;11(8-9):811-9. doi: 10.1016/j.micinf.2009.04.021. Epub 2009 May 7.
Microbes Infect. 2009.
PMID: 19427395
Free PMC article.
Regulated upon activation, normal T-cell expressed, and secreted (RANTES, CCL-5) is an important immunoregulatory mediator that is suppressed in children with malarial anemia (MA). ...Additional experiments in cultured peripheral blood mononuclear cells (PBMC) showed that …
Regulated upon activation, normal T-cell expressed, and secreted (RANTES, CCL-5) is an important immunoregulatory mediator that is su …