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Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children.
Ouma C, Davenport GC, Garcia S, Kempaiah P, Chaudhary A, Were T, Anyona SB, Raballah E, Konah SN, Hittner JB, Vulule JM, Ong'echa JM, Perkins DJ. Ouma C, et al. Among authors: were t. Hum Genet. 2012 Feb;131(2):289-99. doi: 10.1007/s00439-011-1076-8. Epub 2011 Aug 5. Hum Genet. 2012. PMID: 21818580 Free PMC article.
Bacteremia in Kenyan children presenting with malaria.
Were T, Davenport GC, Hittner JB, Ouma C, Vulule JM, Ong'echa JM, Perkins DJ. Were T, et al. J Clin Microbiol. 2011 Feb;49(2):671-6. doi: 10.1128/JCM.01864-10. Epub 2010 Nov 24. J Clin Microbiol. 2011. PMID: 21106789 Free PMC article.
Increased circulating interleukin (IL)-23 in children with malarial anemia: in vivo and in vitro relationship with co-regulatory cytokines IL-12 and IL-10.
Ong'echa JM, Remo AM, Kristoff J, Hittner JB, Were T, Ouma C, Otieno RO, Vulule JM, Keller CC, Awandare GA, Perkins DJ. Ong'echa JM, et al. Among authors: were t. Clin Immunol. 2008 Feb;126(2):211-21. doi: 10.1016/j.clim.2007.08.007. Epub 2007 Oct 22. Clin Immunol. 2008. PMID: 17945537 Free PMC article.
Polymorphic variability in the interleukin (IL)-1beta promoter conditions susceptibility to severe malarial anemia and functional changes in IL-1beta production.
Ouma C, Davenport GC, Awandare GA, Keller CC, Were T, Otieno MF, Vulule JM, Martinson J, Ong'echa JM, Ferrell RE, Perkins DJ. Ouma C, et al. Among authors: were t. J Infect Dis. 2008 Oct 15;198(8):1219-26. doi: 10.1086/592055. J Infect Dis. 2008. PMID: 18781863 Free PMC article.
Because the role played by IL-1beta polymorphic variability in conditioning the immunopathogenesis of severe malarial anemia (SMA) remains undefined, relationships between IL-1beta promoter variants (-31C/T and -511A/G), SMA (hemoglobin [Hb] level <6.0 g/dL), and circul …
Because the role played by IL-1beta polymorphic variability in conditioning the immunopathogenesis of severe malarial anemia (SMA) remains u …
Naturally acquired hemozoin by monocytes promotes suppression of RANTES in children with malarial anemia through an IL-10-dependent mechanism.
Were T, Davenport GC, Yamo EO, Hittner JB, Awandare GA, Otieno MF, Ouma C, Orago AS, Vulule JM, Ong'echa JM, Perkins DJ. Were T, et al. Microbes Infect. 2009 Jul-Aug;11(8-9):811-9. doi: 10.1016/j.micinf.2009.04.021. Epub 2009 May 7. Microbes Infect. 2009. PMID: 19427395 Free PMC article.
Regulated upon activation, normal T-cell expressed, and secreted (RANTES, CCL-5) is an important immunoregulatory mediator that is suppressed in children with malarial anemia (MA). ...Additional experiments in cultured peripheral blood mononuclear cells (PBMC) showed that …
Regulated upon activation, normal T-cell expressed, and secreted (RANTES, CCL-5) is an important immunoregulatory mediator that is su …
A novel functional variant in the stem cell growth factor promoter protects against severe malarial anemia.
Ouma C, Keller CC, Davenport GC, Were T, Konah S, Otieno MF, Hittner JB, Vulule JM, Martinson J, Ong'echa JM, Ferrell RE, Perkins DJ. Ouma C, et al. Among authors: were t. Infect Immun. 2010 Jan;78(1):453-60. doi: 10.1128/IAI.00895-09. Epub 2009 Nov 2. Infect Immun. 2010. PMID: 19884328 Free PMC article.

To extend these investigations, the relationships between a novel SCGF promoter variant (-539C/T, rs7246355), SMA (hemoglobin [Hb] < 6.0 g/dl), and reduced erythropoietic responses (reticulocyte production index [RPI], <2.0) were investigated with Kenyan child

To extend these investigations, the relationships between a novel SCGF promoter variant (-539C/T, rs7246355), SMA (hemoglobin [Hb] &l …
52 results