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A non-comparative randomized phase II study of 2 doses of ATN-224, a copper/zinc superoxide dismutase inhibitor, in patients with biochemically recurrent hormone-naïve prostate cancer.
Lin J, Zahurak M, Beer TM, Ryan CJ, Wilding G, Mathew P, Morris M, Callahan JA, Gordon G, Reich SD, Carducci MA, Antonarakis ES. Lin J, et al. Among authors: gordon g. Urol Oncol. 2013 Jul;31(5):581-8. doi: 10.1016/j.urolonc.2011.04.009. Epub 2011 Aug 4. Urol Oncol. 2013. PMID: 21816640 Free PMC article. Clinical Trial.
Phase I pharmacokinetic and pharmacodynamic study of the oral, small-molecule mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) in patients with advanced cancers.
Adjei AA, Cohen RB, Franklin W, Morris C, Wilson D, Molina JR, Hanson LJ, Gore L, Chow L, Leong S, Maloney L, Gordon G, Simmons H, Marlow A, Litwiler K, Brown S, Poch G, Kane K, Haney J, Eckhardt SG. Adjei AA, et al. Among authors: gordon g. J Clin Oncol. 2008 May 1;26(13):2139-46. doi: 10.1200/JCO.2007.14.4956. Epub 2008 Apr 7. J Clin Oncol. 2008. PMID: 18390968 Free PMC article. Clinical Trial.
Design of CONQUEST, a novel, randomized, placebo-controlled, Phase 2b platform clinical trial to investigate new treatments for patients with early active systemic sclerosis with interstitial lung disease.
Khanna D, Evnin LB, Assassi S, Benton WW, Gordon G, Maslova K, Steffgen J, Maher TM. Khanna D, et al. Among authors: gordon g. J Scleroderma Relat Disord. 2024 Nov 5:23971983241278079. doi: 10.1177/23971983241278079. Online ahead of print. J Scleroderma Relat Disord. 2024. PMID: 39544897 Free PMC article.
Microbial dynamics and pulmonary immune responses in COVID-19 secondary bacterial pneumonia.
Spottiswoode N, Tsitsiklis A, Chu VT, Phan HV, DeVoe C, Love C, Ghale R, Bloomstein J, Zha BS, Maguire CP, Glascock A, Sarma A, Mourani PM, Kalantar KL, Detweiler A, Neff N, Haller SC; COMET Consortium; DeRisi JL, Erle DJ, Hendrickson CM, Kangelaris KN, Krummel MF, Matthay MA, Woodruff PG, Calfee CS, Langelier CR. Spottiswoode N, et al. Nat Commun. 2024 Oct 29;15(1):9339. doi: 10.1038/s41467-024-53566-x. Nat Commun. 2024. PMID: 39472555 Free PMC article.
Assessment of combined α-GAL enzyme activity and lyso-GL3 for Fabry disease screening in women with chronic kidney disease.
Silva CAB, de Carvalho Barreto F, Neto OMV, Lucca LJ, Vieira FA, Gueiros APS, Boger MV, Silva AQ, Guedes FL, Israel KCP, Gordon GEM, Veloso VSP, Sevignani G, Barretto CT, Rosa MG, Pascotto RC, Ennes GS, da Silva Montenegro Malaguti Souza EM, Ribeiro MG, de Andrade LGM. Silva CAB, et al. Among authors: gordon gem. Mol Genet Metab. 2024 Sep-Oct;143(1-2):108565. doi: 10.1016/j.ymgme.2024.108565. Epub 2024 Aug 16. Mol Genet Metab. 2024. PMID: 39182416 Free article.
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification.
Wang L, Guo Q, Acharya S, Zheng X, Huynh V, Whitmore B, Yimit A, Malhotra M, Chatterji S, Rosin N, Labit E, Chipak C, Gorzo K, Haidey J, Elliott DA, Ram T, Zhang Q, Kuipers H, Gordon G, Biernaskie J, Guo J. Wang L, et al. Among authors: gordon g. Nat Neurosci. 2024 Sep;27(9):1708-1720. doi: 10.1038/s41593-024-01726-z. Epub 2024 Aug 5. Nat Neurosci. 2024. PMID: 39103557
1,121 results