Mitsuya H - Search Results

1

Loss of protease dimerization inhibition activity of darunavir is associated with the acquisition of resistance to darunavir by HIV-1.

Koh Y, Aoki M, Danish ML, Aoki-Ogata H, Amano M, Das D, Shafer RW, Ghosh AK, Mitsuya H. Koh Y, et al. Among authors: mitsuya h. J Virol. 2011 Oct;85(19):10079-89. doi: 10.1128/JVI.05121-11. Epub 2011 Aug 3. J Virol. 2011. PMID: 21813613 Free PMC article.

2

Missense mutation of the interleukin-12 receptor beta1 chain-encoding gene is associated with impaired immunity against Mycobacterium avium complex infection.

Sakai T, Matsuoka M, Aoki M, Nosaka K, Mitsuya H. Sakai T, et al. Among authors: mitsuya h. Blood. 2001 May 1;97(9):2688-94. doi: 10.1182/blood.v97.9.2688. Blood. 2001. PMID: 11313259 Free article.

3

Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5.

Maeda K, Yoshimura K, Shibayama S, Habashita H, Tada H, Sagawa K, Miyakawa T, Aoki M, Fukushima D, Mitsuya H. Maeda K, et al. Among authors: mitsuya h. J Biol Chem. 2001 Sep 14;276(37):35194-200. doi: 10.1074/jbc.M105670200. Epub 2001 Jul 13. J Biol Chem. 2001. PMID: 11454872 Free article.

4

A potent human immunodeficiency virus type 1 protease inhibitor, UIC-94003 (TMC-126), and selection of a novel (A28S) mutation in the protease active site.

Yoshimura K, Kato R, Kavlick MF, Nguyen A, Maroun V, Maeda K, Hussain KA, Ghosh AK, Gulnik SV, Erickson JW, Mitsuya H. Yoshimura K, et al. Among authors: mitsuya h. J Virol. 2002 Feb;76(3):1349-58. doi: 10.1128/jvi.76.3.1349-1358.2002. J Virol. 2002. PMID: 11773409 Free PMC article.

5

Reduction of peptide character of HIV protease inhibitors that exhibit nanomolar potency against multidrug resistant HIV-1 strains.

Tamamura H, Koh Y, Ueda S, Sasaki Y, Yamasaki T, Aoki M, Maeda K, Watai Y, Arikuni H, Otaka A, Mitsuya H, Fujii N. Tamamura H, et al. Among authors: mitsuya h. J Med Chem. 2003 Apr 24;46(9):1764-8. doi: 10.1021/jm020537i. J Med Chem. 2003. PMID: 12699395

6

[Allergic reaction against an emulsifier, HCO-60, contained in multamin and enocitabine].

Tatetsu H, Asou N, Nakamura M, Koh Y, Tajiri T, Matsuno F, Horikawa K, Yonemura Y, Mitsuya H. Tatetsu H, et al. Among authors: mitsuya h. Rinsho Ketsueki. 2003 Jul;44(7):471-3. Rinsho Ketsueki. 2003. PMID: 12931567 Japanese.

7

The impact of highly active antiretroviral therapy by the oral route on the CD8 subset in monkeys infected chronically with SHIV 89.6P.

Yoshimura K, Ido E, Akiyama H, Kimura T, Aoki M, Suzuki H, Mitsuya H, Hayami M, Matsushita S. Yoshimura K, et al. Among authors: mitsuya h. J Virol Methods. 2003 Sep;112(1-2):121-8. doi: 10.1016/s0166-0934(03)00201-5. J Virol Methods. 2003. PMID: 12951220

8

Novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI) UIC-94017 (TMC114) with potent activity against multi-PI-resistant human immunodeficiency virus in vitro.

Koh Y, Nakata H, Maeda K, Ogata H, Bilcer G, Devasamudram T, Kincaid JF, Boross P, Wang YF, Tie Y, Volarath P, Gaddis L, Harrison RW, Weber IT, Ghosh AK, Mitsuya H. Koh Y, et al. Among authors: mitsuya h. Antimicrob Agents Chemother. 2003 Oct;47(10):3123-9. doi: 10.1128/AAC.47.10.3123-3129.2003. Antimicrob Agents Chemother. 2003. PMID: 14506019 Free PMC article.

9

Indium-mediated atom-transfer and reductive radical cyclizations of iodoalkynes: synthesis and biological evaluation of HIV-protease inhibitors.

Yanada R, Koh Y, Nishimori N, Matsumura A, Obika S, Mitsuya H, Fujii N, Takemoto Y. Yanada R, et al. Among authors: mitsuya h. J Org Chem. 2004 Apr 2;69(7):2417-22. doi: 10.1021/jo035482m. J Org Chem. 2004. PMID: 15049639

10

Spirodiketopiperazine-based CCR5 inhibitor which preserves CC-chemokine/CCR5 interactions and exerts potent activity against R5 human immunodeficiency virus type 1 in vitro.

Maeda K, Nakata H, Koh Y, Miyakawa T, Ogata H, Takaoka Y, Shibayama S, Sagawa K, Fukushima D, Moravek J, Koyanagi Y, Mitsuya H. Maeda K, et al. Among authors: mitsuya h. J Virol. 2004 Aug;78(16):8654-62. doi: 10.1128/JVI.78.16.8654-8662.2004. J Virol. 2004. PMID: 15280474 Free PMC article.

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