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Page 1
No evidence that extended tracts of homozygosity are associated with Alzheimer's disease.
Sims R, Dwyer S, Harold D, Gerrish A, Hollingworth P, Chapman J, Jones N, Abraham R, Ivanov D, Pahwa JS, Moskvina V, Dowzell K, Thomas C, Stretton A, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuiness B, Todd S, Johnston JA, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Livingston G, Bass NJ, Gurling H, McQuillin A, Jones L, Holmans PA, O'Donovan M, Owen MJ, Williams J. Sims R, et al. Among authors: holmans pa. Am J Med Genet B Neuropsychiatr Genet. 2011 Dec;156B(7):764-71. doi: 10.1002/ajmg.b.31216. Epub 2011 Aug 2. Am J Med Genet B Neuropsychiatr Genet. 2011. PMID: 21812096
Full genome screen for Alzheimer disease: stage II analysis.
Myers A, Wavrant De-Vrieze F, Holmans P, Hamshere M, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J, Ramic D, Knowles H, Morris JC, Williams N, Norton N, Abraham R, Kehoe P, Williams H, Rudrasingham V, Rice F, Giles P, Tunstall N, Jones L, Lovestone S, Williams J, Owen MJ, Hardy J, Goate A. Myers A, et al. Am J Med Genet. 2002 Mar 8;114(2):235-44. doi: 10.1002/ajmg.10183. Am J Med Genet. 2002. PMID: 11857588
Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD.
Myers AJ, Marshall H, Holmans P, Compton D, Crook RJ, Mander AP, Nowotny P, Smemo S, Dunstan M, Jehu L, Wang JC, Hamshere M, Morris JC, Norton J, Chakraventy S, Tunstall N, Lovestone S, Petersen R, O'Donovan M, Jones L, Williams J, Owen MJ, Hardy J, Goate A. Myers AJ, et al. Am J Med Genet B Neuropsychiatr Genet. 2004 Jan 1;124B(1):29-37. doi: 10.1002/ajmg.b.20036. Am J Med Genet B Neuropsychiatr Genet. 2004. PMID: 14681909
Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease.
Busby V, Goossens S, Nowotny P, Hamilton G, Smemo S, Harold D, Turic D, Jehu L, Myers A, Womick M, Woo D, Compton D, Doil LM, Tacey KM, Lau KF, Al-Saraj S, Killick R, Pickering-Brown S, Moore P, Hollingworth P, Archer N, Foy C, Walter S, Lendon C, Iwatsubo T, Morris JC, Norton J, Mann D, Janssens B, Hardy J, O'Donovan M, Jones L, Williams J, Holmans P, Owen MJ, Grupe A, Powell J, van Hengel J, Goate A, Van Roy F, Lovestone S. Busby V, et al. Neuromolecular Med. 2004;5(2):133-46. doi: 10.1385/NMM:5:2:133. Neuromolecular Med. 2004. PMID: 15075440
Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family.
Li Y, Nowotny P, Holmans P, Smemo S, Kauwe JS, Hinrichs AL, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Gogic G, Chan J, Cravchik A, Ross D, Lau K, Kwok S, Chang SY, Catanese J, Sninsky J, White TJ, Hardy J, Powell J, Lovestone S, Morris JC, Thal L, Owen M, Williams J, Goate A, Grupe A. Li Y, et al. Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15688-93. doi: 10.1073/pnas.0403535101. Epub 2004 Oct 26. Proc Natl Acad Sci U S A. 2004. PMID: 15507493 Free PMC article.
Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease.
Li Y, Hollingworth P, Moore P, Foy C, Archer N, Powell J, Nowotny P, Holmans P, O'Donovan M, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Lau K, Cantanese J, Sninsky J, Hardy J, Thal L, Morris JC, Goate A, Lovestone S, Owen M, Williams J, Grupe A. Li Y, et al. Hum Mutat. 2005 Mar;25(3):270-7. doi: 10.1002/humu.20138. Hum Mutat. 2005. PMID: 15714520
Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease.
Holmans P, Hamshere M, Hollingworth P, Rice F, Tunstall N, Jones S, Moore P, Wavrant DeVrieze F, Myers A, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J, Ramic D, Williams N, Norton N, Abraham R, Kehoe P, Williams H, Rudrasingham V, O'Donovan M, Jones L, Hardy J, Goate A, Lovestone S, Owen M, Williams J. Holmans P, et al. Am J Med Genet B Neuropsychiatr Genet. 2005 May 5;135B(1):24-32. doi: 10.1002/ajmg.b.30114. Am J Med Genet B Neuropsychiatr Genet. 2005. PMID: 15729734
345 results