Davtyan H - Search Results

1

The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer's disease.

Davtyan H, Ghochikyan A, Cadagan R, Zamarin D, Petrushina I, Movsesyan N, Martinez-Sobrido L, Albrecht RA, García-Sastre A, Agadjanyan MG. Davtyan H, et al. J Transl Med. 2011 Aug 1;9:127. doi: 10.1186/1479-5876-9-127. J Transl Med. 2011. PMID: 21806809 Free PMC article.

2

Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease.

McQuade A, Kang YJ, Hasselmann J, Jairaman A, Sotelo A, Coburn M, Shabestari SK, Chadarevian JP, Fote G, Tu CH, Danhash E, Silva J, Martinez E, Cotman C, Prieto GA, Thompson LM, Steffan JS, Smith I, Davtyan H, Cahalan M, Cho H, Blurton-Jones M. McQuade A, et al. Among authors: davtyan h. Nat Commun. 2023 Mar 2;14(1):1194. doi: 10.1038/s41467-023-36930-1. Nat Commun. 2023. PMID: 36864071 Free PMC article. No abstract available.

3

CRISPR generation of CSF1R-G795A human microglia for robust microglia replacement in a chimeric mouse model.

Chadarevian JP, Davtyan H, Lombroso SI, Bennett FC, Blurton-Jones M. Chadarevian JP, et al. Among authors: davtyan h. STAR Protoc. 2023 Sep 15;4(3):102490. doi: 10.1016/j.xpro.2023.102490. Epub 2023 Jul 29. STAR Protoc. 2023. PMID: 37516973 Free PMC article.

4

Engineering an inhibitor-resistant human CSF1R variant for microglia replacement.

Chadarevian JP, Lombroso SI, Peet GC, Hasselmann J, Tu C, Marzan DE, Capocchi J, Purnell FS, Nemec KM, Lahian A, Escobar A, England W, Chaluvadi S, O'Brien CA, Yaqoob F, Aisenberg WH, Porras-Paniagua M, Bennett ML, Davtyan H, Spitale RC, Blurton-Jones M, Bennett FC. Chadarevian JP, et al. Among authors: davtyan h. J Exp Med. 2023 Mar 6;220(3):e20220857. doi: 10.1084/jem.20220857. Epub 2022 Dec 30. J Exp Med. 2023. PMID: 36584406 Free PMC article.

5

Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3.

Haukedal H, Syshøj Lorenzen S, Winther Westi E, Corsi GI, Gadekar VP, McQuade A, Davtyan H, Doncheva NT, Schmid B, Chandrasekaran A, Seemann SE, Cirera S, Blurton-Jones M, Meyer M, Gorodkin J, Aldana BI, Freude K. Haukedal H, et al. Among authors: davtyan h. Brain Behav Immun. 2023 Oct;113:353-373. doi: 10.1016/j.bbi.2023.07.024. Epub 2023 Aug 3. Brain Behav Immun. 2023. PMID: 37543250 Free article.

6

DNA, but not protein vaccine based on mutated BORIS antigen significantly inhibits tumor growth and prolongs the survival of mice.

Mkrtichyan M, Ghochikyan A, Loukinov D, Davtyan H, Ichim TE, Cribbs DH, Lobanenkov VV, Agadjanyan MG. Mkrtichyan M, et al. Among authors: davtyan h. Gene Ther. 2008 Jan;15(1):61-4. doi: 10.1038/sj.gt.3303044. Epub 2007 Nov 1. Gene Ther. 2008. PMID: 17972923 Free PMC article.

7

Alzheimer's disease peptide epitope vaccine reduces insoluble but not soluble/oligomeric Abeta species in amyloid precursor protein transgenic mice.

Petrushina I, Ghochikyan A, Mktrichyan M, Mamikonyan G, Movsesyan N, Davtyan H, Patel A, Head E, Cribbs DH, Agadjanyan MG. Petrushina I, et al. Among authors: davtyan h. J Neurosci. 2007 Nov 14;27(46):12721-31. doi: 10.1523/JNEUROSCI.3201-07.2007. J Neurosci. 2007. PMID: 18003852 Free PMC article.

8

Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy.

Movsesyan N, Ghochikyan A, Mkrtichyan M, Petrushina I, Davtyan H, Olkhanud PB, Head E, Biragyn A, Cribbs DH, Agadjanyan MG. Movsesyan N, et al. Among authors: davtyan h. PLoS One. 2008 May 7;3(5):e2124. doi: 10.1371/journal.pone.0002124. PLoS One. 2008. PMID: 18461171 Free PMC article.

9

DNA prime-protein boost increased the titer, avidity and persistence of anti-Abeta antibodies in wild-type mice.

Davtyan H, Mkrtichyan M, Movsesyan N, Petrushina I, Mamikonyan G, Cribbs DH, Agadjanyan MG, Ghochikyan A. Davtyan H, et al. Gene Ther. 2010 Feb;17(2):261-71. doi: 10.1038/gt.2009.140. Epub 2009 Oct 29. Gene Ther. 2010. PMID: 19865176 Free PMC article.

10

Low concentrations of anti-Aβ antibodies generated in Tg2576 mice by DNA epitope vaccine fused with 3C3d molecular adjuvant do not affect AD pathology.

Movsesyan N, Davtyan H, Mkrtichyan M, Petrushina I, Tiraturyan T, Ross T, Agadjanyan MG, Ghochikyan A, Cribbs DH. Movsesyan N, et al. Among authors: davtyan h. Hum Gene Ther. 2010 Nov;21(11):1569-76. doi: 10.1089/hum.2009.219. Hum Gene Ther. 2010. PMID: 20528468 Free PMC article.

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