Watson AJ - Search Results

1

Characterization of a new trabectedin-resistant myxoid liposarcoma cell line that shows collateral sensitivity to methylating agents.

Uboldi S, Bernasconi S, Romano M, Marchini S, Fuso Nerini I, Damia G, Ganzinelli M, Marangon E, Sala F, Clivio L, Chiorino G, Di Giandomenico S, Rocchi M, Capozzi O, Margison GP, Watson AJ, Caccuri AM, Pastore A, Fossati A, Mantovani R, Grosso F, Tercero JC, Erba E, D'Incalci M. Uboldi S, et al. Among authors: watson aj. Int J Cancer. 2012 Jul 1;131(1):59-69. doi: 10.1002/ijc.26340. Epub 2011 Aug 30. Int J Cancer. 2012. PMID: 21805478

2

Depletion of O6-alkylguanine-DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumour cells.

Baer JC, Freeman AA, Newlands ES, Watson AJ, Rafferty JA, Margison GP. Baer JC, et al. Among authors: watson aj. Br J Cancer. 1993 Jun;67(6):1299-302. doi: 10.1038/bjc.1993.241. Br J Cancer. 1993. PMID: 8512814 Free PMC article.

3

O6-alkylguanine-DNA alkyltransferase attenuates triazene-induced cytotoxicity and tumor cell immunogenicity in murine L1210 leukemia.

Graziani G, Faraoni I, Grohmann U, Bianchi R, Binaglia L, Margison GP, Watson AJ, Orlando L, Bonmassar E, D'Atri S. Graziani G, et al. Among authors: watson aj. Cancer Res. 1995 Dec 15;55(24):6231-6. Cancer Res. 1995. PMID: 8521419

4

O6-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenografts.

Clemons M, Kelly J, Watson AJ, Howell A, McElhinney RS, McMurry TB, Margison GP. Clemons M, et al. Among authors: watson aj. Br J Cancer. 2005 Nov 14;93(10):1152-6. doi: 10.1038/sj.bjc.6602833. Br J Cancer. 2005. PMID: 16278661 Free PMC article.

5

A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer.

Khan OA, Ranson M, Michael M, Olver I, Levitt NC, Mortimer P, Watson AJ, Margison GP, Midgley R, Middleton MR. Khan OA, et al. Among authors: watson aj. Br J Cancer. 2008 May 20;98(10):1614-8. doi: 10.1038/sj.bjc.6604366. Epub 2008 May 13. Br J Cancer. 2008. PMID: 18475294 Free PMC article. Clinical Trial.

6

A phase I trial of lomeguatrib and irinotecan in metastatic colorectal cancer.

Sabharwal A, Corrie PG, Midgley RS, Palmer C, Brady J, Mortimer P, Watson AJ, Margison GP, Middleton MR. Sabharwal A, et al. Among authors: watson aj. Cancer Chemother Pharmacol. 2010 Oct;66(5):829-35. doi: 10.1007/s00280-009-1225-0. Epub 2009 Dec 29. Cancer Chemother Pharmacol. 2010. PMID: 20039040 Clinical Trial.

7

Macrophage inflammatory protein 1alpha attenuates the toxic effects of temozolomide in human bone marrow granulocyte-macrophage colony-forming cells.

Clemons M, Watson A, Howell A, Chang J, Heyworth C, Lord B, Testa N, Dexter TM, Margison G. Clemons M, et al. Clin Cancer Res. 2000 Mar;6(3):966-70. Clin Cancer Res. 2000. PMID: 10741722

8

Folate deficiency alters hepatic and colon MGMT and OGG-1 DNA repair protein expression in rats but has no effect on genome-wide DNA methylation.

Duthie SJ, Grant G, Pirie LP, Watson AJ, Margison GP. Duthie SJ, et al. Among authors: watson aj. Cancer Prev Res (Phila). 2010 Jan;3(1):92-100. doi: 10.1158/1940-6207.CAPR-09-0231. Cancer Prev Res (Phila). 2010. PMID: 20051376 Free PMC article.

9

O6-benzylguanine increases the sensitivity of human primary bone marrow cells to the cytotoxic effects of temozolomide.

Fairbairn LJ, Watson AJ, Rafferty JA, Elder RH, Margison GP. Fairbairn LJ, et al. Among authors: watson aj. Exp Hematol. 1995 Feb;23(2):112-6. Exp Hematol. 1995. PMID: 7828668

10

Attenuation of O(6)-methylguanine-DNA methyltransferase activity and mRNA levels by cisplatin and temozolomide in jurkat cells.

D'Atri S, Graziani G, Lacal PM, Nisticò V, Gilberti S, Faraoni I, Watson AJ, Bonmassar E, Margison GP. D'Atri S, et al. Among authors: watson aj. J Pharmacol Exp Ther. 2000 Aug;294(2):664-71. J Pharmacol Exp Ther. 2000. PMID: 10900246

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