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Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model.
Moore RG, Lange TS, Robinson K, Kim KK, Uzun A, Horan TC, Kawar N, Yano N, Chu SR, Mao Q, Brard L, DePaepe ME, Padbury JF, Arnold LA, Brodsky A, Shen TL, Singh RK. Moore RG, et al. Among authors: arnold la. PLoS One. 2012;7(4):e34443. doi: 10.1371/journal.pone.0034443. Epub 2012 Apr 3. PLoS One. 2012. PMID: 22509304 Free PMC article.
PT19c, Another Nonhypercalcemic Vitamin D2 Derivative, Demonstrates Antitumor Efficacy in Epithelial Ovarian and Endometrial Cancer Models.
Kawar N, Maclaughlan S, Horan TC, Uzun A, Lange TS, Kim KK, Hopson R, Singh AP, Sidhu PS, Glass KA, Shaw S, Padbury JF, Vorsa N, Arnold LA, Moore RG, Brard L, Singh RK. Kawar N, et al. Among authors: arnold la. Genes Cancer. 2013 Nov;4(11-12):524-34. doi: 10.1177/1947601913507575. Genes Cancer. 2013. PMID: 24386512 Free PMC article.
Antitumor Activity of 3-Indolylmethanamines 31B and PS121912.
Guthrie ML, Sidhu PS, Hill EK, Horan TC, Nandhikonda P, Teske KA, Yuan NY, Sidorko M, Rodali R, Cook JM, Han L, Silvaggi NR, Bikle DD, Moore RG, Singh RK, Arnold LA. Guthrie ML, et al. Among authors: arnold la. Anticancer Res. 2015 Nov;35(11):6001-7. Anticancer Res. 2015. PMID: 26504023 Free PMC article.
Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors In Vivo.
Khazan N, Kim KK, Hansen JN, Singh NA, Moore T, Snyder CWA, Pandita R, Strawderman M, Fujihara M, Takamura Y, Jian Y, Battaglia N, Yano N, Teramoto Y, Arnold LA, Hopson R, Kishor K, Nayak S, Ojha D, Sharon A, Ashton JM, Wang J, Milano MT, Miyamoto H, Linehan DC, Gerber SA, Kawar N, Singh AP, Tabdanov ED, Dokholyan NV, Kakuta H, Jurutka PW, Schor NF, Rowswell-Turner RB, Singh RK, Moore RG. Khazan N, et al. Among authors: arnold la. J Med Chem. 2022 Apr 28;65(8):6039-6055. doi: 10.1021/acs.jmedchem.1c01878. Epub 2022 Apr 11. J Med Chem. 2022. PMID: 35404047 Free PMC article.
Development of novel Vitamin D Receptor-Coactivator Inhibitors.
Sidhu PS, Nassif N, McCallum MM, Teske K, Feleke B, Yuan NY, Nandhikonda P, Cook JM, Singh RK, Bikle DD, Arnold LA. Sidhu PS, et al. Among authors: arnold la. ACS Med Chem Lett. 2014 Feb 13;5(2):199-204. doi: 10.1021/ml400462j. ACS Med Chem Lett. 2014. PMID: 24799995 Free PMC article.
Anticancer activity of VDR-coregulator inhibitor PS121912.
Sidhu PS, Teske K, Feleke B, Yuan NY, Guthrie ML, Fernstrum GB, Vyas ND, Han L, Preston J, Bogart JW, Silvaggi NR, Cook JM, Singh RK, Bikle DD, Arnold LA. Sidhu PS, et al. Among authors: arnold la. Cancer Chemother Pharmacol. 2014 Oct;74(4):787-98. doi: 10.1007/s00280-014-2549-y. Epub 2014 Aug 9. Cancer Chemother Pharmacol. 2014. PMID: 25107568 Free PMC article.
Peroxisome proliferation-activated receptor δ agonist GW0742 interacts weakly with multiple nuclear receptors, including the vitamin D receptor.
Nandhikonda P, Yasgar A, Baranowski AM, Sidhu PS, McCallum MM, Pawlak AJ, Teske K, Feleke B, Yuan NY, Kevin C, Bikle DD, Ayers SD, Webb P, Rai G, Simeonov A, Jadhav A, Maloney D, Arnold LA. Nandhikonda P, et al. Among authors: arnold la. Biochemistry. 2013 Jun 18;52(24):4193-203. doi: 10.1021/bi400321p. Epub 2013 Jun 10. Biochemistry. 2013. PMID: 23713684 Free PMC article.
118 results