Ogilvie BW - Search Results

1

The proton pump inhibitor, omeprazole, but not lansoprazole or pantoprazole, is a metabolism-dependent inhibitor of CYP2C19: implications for coadministration with clopidogrel.

Ogilvie BW, Yerino P, Kazmi F, Buckley DB, Rostami-Hodjegan A, Paris BL, Toren P, Parkinson A. Ogilvie BW, et al. Drug Metab Dispos. 2011 Nov;39(11):2020-33. doi: 10.1124/dmd.111.041293. Epub 2011 Jul 27. Drug Metab Dispos. 2011. PMID: 21795468

2

Glucuronidation converts gemfibrozil to a potent, metabolism-dependent inhibitor of CYP2C8: implications for drug-drug interactions.

Ogilvie BW, Zhang D, Li W, Rodrigues AD, Gipson AE, Holsapple J, Toren P, Parkinson A. Ogilvie BW, et al. Drug Metab Dispos. 2006 Jan;34(1):191-7. doi: 10.1124/dmd.105.007633. Epub 2005 Nov 18. Drug Metab Dispos. 2006. PMID: 16299161

3

In vitro inhibition and induction of human liver cytochrome p450 enzymes by milnacipran.

Paris BL, Ogilvie BW, Scheinkoenig JA, Ndikum-Moffor F, Gibson R, Parkinson A. Paris BL, et al. Among authors: ogilvie bw. Drug Metab Dispos. 2009 Oct;37(10):2045-54. doi: 10.1124/dmd.109.028274. Epub 2009 Jul 16. Drug Metab Dispos. 2009. PMID: 19608694

4

System-dependent outcomes during the evaluation of drug candidates as inhibitors of cytochrome P450 (CYP) and uridine diphosphate glucuronosyltransferase (UGT) enzymes: human hepatocytes versus liver microsomes versus recombinant enzymes.

Parkinson A, Kazmi F, Buckley DB, Yerino P, Ogilvie BW, Paris BL. Parkinson A, et al. Among authors: ogilvie bw. Drug Metab Pharmacokinet. 2010;25(1):16-27. doi: 10.2133/dmpk.25.16. Drug Metab Pharmacokinet. 2010. PMID: 20208386 Free article. Review.

5

An evaluation of the dilution method for identifying metabolism-dependent inhibitors of cytochrome P450 enzymes.

Parkinson A, Kazmi F, Buckley DB, Yerino P, Paris BL, Holsapple J, Toren P, Otradovec SM, Ogilvie BW. Parkinson A, et al. Among authors: ogilvie bw. Drug Metab Dispos. 2011 Aug;39(8):1370-87. doi: 10.1124/dmd.111.038596. Epub 2011 Apr 27. Drug Metab Dispos. 2011. PMID: 21525169

6

The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments.

Haupt LJ, Kazmi F, Ogilvie BW, Buckley DB, Smith BD, Leatherman S, Paris B, Parkinson O, Parkinson A. Haupt LJ, et al. Among authors: ogilvie bw. Drug Metab Dispos. 2015 Nov;43(11):1744-50. doi: 10.1124/dmd.115.066597. Epub 2015 Sep 9. Drug Metab Dispos. 2015. PMID: 26354951

7

An Assessment of the In Vitro Inhibition of Cytochrome P450 Enzymes, UDP-Glucuronosyltransferases, and Transporters by Phosphodiester- or Phosphorothioate-Linked Oligonucleotides.

Kazmi F, Yerino P, McCoy C, Parkinson A, Buckley DB, Ogilvie BW. Kazmi F, et al. Among authors: ogilvie bw. Drug Metab Dispos. 2018 Aug;46(8):1066-1074. doi: 10.1124/dmd.118.081729. Epub 2018 May 7. Drug Metab Dispos. 2018. PMID: 29735754

8

An in vitro evaluation of the victim and perpetrator potential of the anticancer agent laromustine (VNP40101M), based on reaction phenotyping and inhibition and induction of cytochrome P450 enzymes.

Nassar AE, King I, Paris BL, Haupt L, Ndikum-Moffor F, Campbell R, Usuki E, Skibbe J, Brobst D, Ogilvie BW, Parkinson A. Nassar AE, et al. Among authors: ogilvie bw. Drug Metab Dispos. 2009 Sep;37(9):1922-30. doi: 10.1124/dmd.109.027516. Epub 2009 Jun 11. Drug Metab Dispos. 2009. PMID: 19520774

9

Evaluation of Ketoconazole and Its Alternative Clinical CYP3A4/5 Inhibitors as Inhibitors of Drug Transporters: The In Vitro Effects of Ketoconazole, Ritonavir, Clarithromycin, and Itraconazole on 13 Clinically-Relevant Drug Transporters.

Vermeer LM, Isringhausen CD, Ogilvie BW, Buckley DB. Vermeer LM, et al. Among authors: ogilvie bw. Drug Metab Dispos. 2016 Mar;44(3):453-9. doi: 10.1124/dmd.115.067744. Epub 2015 Dec 14. Drug Metab Dispos. 2016. PMID: 26668209

10

On the mechanism of hepatocarcinogenesis of benzodiazepines: evidence that diazepam and oxazepam are CYP2B inducers in rats, and both CYP2B and CYP4A inducers in mice.

Parkinson A, Leonard N, Draper A, Ogilvie BW. Parkinson A, et al. Among authors: ogilvie bw. Drug Metab Rev. 2006;38(1-2):235-59. doi: 10.1080/03602530600570081. Drug Metab Rev. 2006. PMID: 16684660

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