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Are all KRAS mutations created equal?
Stinchcombe TE, Der CJ. Stinchcombe TE, et al. Among authors: der cj. Lancet Oncol. 2011 Aug;12(8):717-8. doi: 10.1016/S1470-2045(11)70200-5. Epub 2011 Jul 22. Lancet Oncol. 2011. PMID: 21782508 No abstract available.
KRAS: feeding pancreatic cancer proliferation.
Bryant KL, Mancias JD, Kimmelman AC, Der CJ. Bryant KL, et al. Among authors: der cj. Trends Biochem Sci. 2014 Feb;39(2):91-100. doi: 10.1016/j.tibs.2013.12.004. Epub 2014 Jan 2. Trends Biochem Sci. 2014. PMID: 24388967 Free PMC article. Review.
Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression.
Hayes TK, Neel NF, Hu C, Gautam P, Chenard M, Long B, Aziz M, Kassner M, Bryant KL, Pierobon M, Marayati R, Kher S, George SD, Xu M, Wang-Gillam A, Samatar AA, Maitra A, Wennerberg K, Petricoin EF 3rd, Yin HH, Nelkin B, Cox AD, Yeh JJ, Der CJ. Hayes TK, et al. Among authors: der cj. Cancer Cell. 2016 Jan 11;29(1):75-89. doi: 10.1016/j.ccell.2015.11.011. Epub 2015 Dec 24. Cancer Cell. 2016. PMID: 26725216 Free PMC article.
RAS isoforms and mutations in cancer at a glance.
Hobbs GA, Der CJ, Rossman KL. Hobbs GA, et al. Among authors: der cj. J Cell Sci. 2016 Apr 1;129(7):1287-92. doi: 10.1242/jcs.182873. Epub 2016 Mar 16. J Cell Sci. 2016. PMID: 26985062 Free PMC article. Review.
A Landscape of Therapeutic Cooperativity in KRAS Mutant Cancers Reveals Principles for Controlling Tumor Evolution.
Anderson GR, Winter PS, Lin KH, Nussbaum DP, Cakir M, Stein EM, Soderquist RS, Crawford L, Leeds JC, Newcomb R, Stepp P, Yip C, Wardell SE, Tingley JP, Ali M, Xu M, Ryan M, McCall SJ, McRee AJ, Counter CM, Der CJ, Wood KC. Anderson GR, et al. Among authors: der cj. Cell Rep. 2017 Jul 25;20(4):999-1015. doi: 10.1016/j.celrep.2017.07.006. Cell Rep. 2017. PMID: 28746882 Free PMC article.
394 results