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Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines.
Liu F, Barsyte-Lovejoy D, Allali-Hassani A, He Y, Herold JM, Chen X, Yates CM, Frye SV, Brown PJ, Huang J, Vedadi M, Arrowsmith CH, Jin J. Liu F, et al. Among authors: jin j. J Med Chem. 2011 Sep 8;54(17):6139-50. doi: 10.1021/jm200903z. Epub 2011 Aug 5. J Med Chem. 2011. PMID: 21780790 Free PMC article.
Oxazolidinones as novel human CCR8 antagonists.
Jin J, Wang Y, Wang F, Kerns JK, Vinader VM, Hancock AP, Lindon MJ, Stevenson GI, Morrow DM, Rao P, Nguyen C, Barrett VJ, Browning C, Hartmann G, Andrew DP, Sarau HM, Foley JJ, Jurewicz AJ, Fornwald JA, Harker AJ, Moore ML, Rivero RA, Belmonte KE, Connor HE. Jin J, et al. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1722-5. doi: 10.1016/j.bmcl.2006.12.076. Epub 2006 Dec 24. Bioorg Med Chem Lett. 2007. PMID: 17267215
2-Aminomethyl piperidines as novel urotensin-II receptor antagonists.
Jin J, Wang Y, Wang F, Shi D, Erhard KF, Wu Z, Guida BF, Lawrence SK, Behm DJ, Disa J, Vaidya KS, Evans C, McMillan LJ, Rivero RA, Neeb MJ, Douglas SA. Jin J, et al. Bioorg Med Chem Lett. 2008 May 1;18(9):2860-4. doi: 10.1016/j.bmcl.2008.03.078. Epub 2008 Apr 8. Bioorg Med Chem Lett. 2008. PMID: 18420409
Muscarinic acetylcholine receptor antagonists: SAR and optimization of tyrosine ureas.
Jin J, Wang Y, Shi D, Wang F, Fu W, Davis RS, Jin Q, Foley JJ, Sarau HM, Morrow DM, Moore ML, Rivero RA, Palovich M, Salmon M, Belmonte KE, Busch-Petersen J. Jin J, et al. Among authors: jin q. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5481-6. doi: 10.1016/j.bmcl.2008.09.020. Epub 2008 Sep 10. Bioorg Med Chem Lett. 2008. PMID: 18818072
Camphor sulfonamide derivatives as novel, potent and selective CXCR3 antagonists.
Wang Y, Busch-Petersen J, Wang F, Kiesow TJ, Graybill TL, Jin J, Yang Z, Foley JJ, Hunsberger GE, Schmidt DB, Sarau HM, Capper-Spudich EA, Wu Z, Fisher LS, McQueney MS, Rivero RA, Widdowson KL. Wang Y, et al. Among authors: jin j. Bioorg Med Chem Lett. 2009 Jan 1;19(1):114-8. doi: 10.1016/j.bmcl.2008.11.008. Epub 2008 Nov 6. Bioorg Med Chem Lett. 2009. PMID: 19014886
M3 muscarinic acetylcholine receptor antagonists: SAR and optimization of bi-aryl amines.
Budzik B, Wang Y, Shi D, Wang F, Xie H, Wan Z, Zhu C, Foley JJ, Nuthulaganti P, Kallal LA, Sarau HM, Morrow DM, Moore ML, Rivero RA, Palovich M, Salmon M, Belmonte KE, Laine DI, Jin J. Budzik B, et al. Among authors: jin j. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1686-90. doi: 10.1016/j.bmcl.2009.01.098. Epub 2009 Feb 4. Bioorg Med Chem Lett. 2009. PMID: 19243945
Discovery of novel aminothiadiazole amides as selective EP(3) receptor antagonists.
Hilfiker MA, Wang N, Hou X, Du Z, Pullen MA, Nord M, Nagilla R, Fries HE, Wu CW, Sulpizio AC, Jaworski JP, Morrow D, Edwards RM, Jin J. Hilfiker MA, et al. Among authors: jin j. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4292-5. doi: 10.1016/j.bmcl.2009.05.074. Epub 2009 May 27. Bioorg Med Chem Lett. 2009. PMID: 19487124
13,365 results
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