Donehower LA - Search Results

1

Absence of Wip1 partially rescues Atm deficiency phenotypes in mice.

Darlington Y, Nguyen TA, Moon SH, Herron A, Rao P, Zhu C, Lu X, Donehower LA. Darlington Y, et al. Among authors: donehower la. Oncogene. 2012 Mar 1;31(9):1155-65. doi: 10.1038/onc.2011.303. Epub 2011 Jul 18. Oncogene. 2012. PMID: 21765465 Free PMC article.

2

The type 2C phosphatase Wip1: an oncogenic regulator of tumor suppressor and DNA damage response pathways.

Lu X, Nguyen TA, Moon SH, Darlington Y, Sommer M, Donehower LA. Lu X, et al. Among authors: donehower la. Cancer Metastasis Rev. 2008 Jun;27(2):123-35. doi: 10.1007/s10555-008-9127-x. Cancer Metastasis Rev. 2008. PMID: 18265945 Free PMC article. Review.

3

The oncogenic phosphatase WIP1 negatively regulates nucleotide excision repair.

Nguyen TA, Slattery SD, Moon SH, Darlington YF, Lu X, Donehower LA. Nguyen TA, et al. Among authors: donehower la. DNA Repair (Amst). 2010 Jul 1;9(7):813-23. doi: 10.1016/j.dnarep.2010.04.005. Epub 2010 May 6. DNA Repair (Amst). 2010. PMID: 20451471 Free PMC article.

4

Dephosphorylation of γ-H2AX by WIP1: an important homeostatic regulatory event in DNA repair and cell cycle control.

Moon SH, Nguyen TA, Darlington Y, Lu X, Donehower LA. Moon SH, et al. Among authors: donehower la. Cell Cycle. 2010 Jun 1;9(11):2092-6. doi: 10.4161/cc.9.11.11810. Epub 2010 Jun 1. Cell Cycle. 2010. PMID: 20495376 Free PMC article.

5

Dual-specificity phosphatase 26 is a novel p53 phosphatase and inhibits p53 tumor suppressor functions in human neuroblastoma.

Shang X, Vasudevan SA, Yu Y, Ge N, Ludwig AD, Wesson CL, Wang K, Burlingame SM, Zhao YJ, Rao PH, Lu X, Russell HV, Okcu MF, Hicks MJ, Shohet JM, Donehower LA, Nuchtern JG, Yang J. Shang X, et al. Among authors: donehower la. Oncogene. 2010 Sep 2;29(35):4938-46. doi: 10.1038/onc.2010.244. Epub 2010 Jun 21. Oncogene. 2010. PMID: 20562916 Free PMC article.

6

Activities of wildtype and mutant p53 in suppression of homologous recombination as measured by a retroviral vector system.

Lu X, Lozano G, Donehower LA. Lu X, et al. Among authors: donehower la. Mutat Res. 2003 Jan 28;522(1-2):69-83. doi: 10.1016/s0027-5107(02)00261-0. Mutat Res. 2003. PMID: 12517413

7

Homeostatic regulation of base excision repair by a p53-induced phosphatase: linking stress response pathways with DNA repair proteins.

Lu X, Nguyen TA, Appella E, Donehower LA. Lu X, et al. Among authors: donehower la. Cell Cycle. 2004 Nov;3(11):1363-6. doi: 10.4161/cc.3.11.1241. Epub 2004 Nov 15. Cell Cycle. 2004. PMID: 15539943

8

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints.

Lu X, Nannenga B, Donehower LA. Lu X, et al. Among authors: donehower la. Genes Dev. 2005 May 15;19(10):1162-74. doi: 10.1101/gad.1291305. Epub 2005 May 3. Genes Dev. 2005. PMID: 15870257 Free PMC article.

9

Reversal of the ATM/ATR-mediated DNA damage response by the oncogenic phosphatase PPM1D.

Lu X, Nguyen TA, Donehower LA. Lu X, et al. Among authors: donehower la. Cell Cycle. 2005 Aug;4(8):1060-4. Epub 2005 Aug 26. Cell Cycle. 2005. PMID: 15970689

10

Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice.

Nannenga B, Lu X, Dumble M, Van Maanen M, Nguyen TA, Sutton R, Kumar TR, Donehower LA. Nannenga B, et al. Among authors: donehower la. Mol Carcinog. 2006 Aug;45(8):594-604. doi: 10.1002/mc.20195. Mol Carcinog. 2006. PMID: 16652371

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