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Phase I study of Oral gemcitabine prodrug (LY2334737) alone and in combination with erlotinib in patients with advanced solid tumors.
Koolen SL, Witteveen PO, Jansen RS, Langenberg MH, Kronemeijer RH, Nol A, Garcia-Ribas I, Callies S, Benhadji KA, Slapak CA, Beijnen JH, Voest EE, Schellens JH. Koolen SL, et al. Clin Cancer Res. 2011 Sep 15;17(18):6071-82. doi: 10.1158/1078-0432.CCR-11-0353. Epub 2011 Jul 13. Clin Cancer Res. 2011. PMID: 21753156 Clinical Trial.
Hepatotoxicity in patients with non-small cell lung cancer treated with sotorasib after prior immunotherapy: a comprehensive clinical and pharmacokinetic analysis.
Ernst SM, Hofman MM, van der Horst TE, Paats MS, Heijboer FWJ, Aerts JGJV, Dumoulin DW, Cornelissen R, von der Thüsen JH, de Bruijn P, Hoop EO, Mathijssen RHJ, Koolen SLW, Dingemans AC. Ernst SM, et al. EBioMedicine. 2024 Apr;102:105074. doi: 10.1016/j.ebiom.2024.105074. Epub 2024 Mar 19. EBioMedicine. 2024. PMID: 38507877 Free PMC article.
The OCT2/MATE1 Interaction Between Trifluridine, Metformin and Cimetidine: A Crossover Pharmacokinetic Study.
Guchelaar NAD, Buck SAJ, van Doorn L, Hussaarts KGAM, Sandberg Y, van der Padt-Pruijsten A, van Alphen RJ, Poppe-Manenschijn L, Vleut I, de Bruijn P, van Leeuwen RWF, Mostert B, Eskens FALM, Oomen-de Hoop E, Koolen SLW, Mathijssen RHJ. Guchelaar NAD, et al. Clin Pharmacokinet. 2024 Jul;63(7):1037-1044. doi: 10.1007/s40262-024-01390-3. Epub 2024 Jun 28. Clin Pharmacokinet. 2024. PMID: 38951433 Free PMC article. Clinical Trial.
Intraperitoneal pharmacokinetics of systemic oxaliplatin, 5-fluorouracil and bevacizumab in patients with colorectal peritoneal metastases.
Rietveld PCS, Guchelaar NAD, van Eerden RAG, de Boer NL, de Bruijn P, Sassen SDT, Madsen EVE, Koch BCP, Verhoef C, Burger JWA, Mathijssen RHJ, Koolen SLW. Rietveld PCS, et al. Biomed Pharmacother. 2024 Jul;176:116820. doi: 10.1016/j.biopha.2024.116820. Epub 2024 May 28. Biomed Pharmacother. 2024. PMID: 38810398 Free article. Clinical Trial.
Radiolabeling and quality control of therapeutic radiopharmaceuticals: optimization, clinical implementation and comparison of radio-TLC/HPLC analysis, demonstrated by [177Lu]Lu-PSMA.
Hooijman EL, Ntihabose CM, Reuvers TGA, Nonnekens J, Aalbersberg EA, van de Merbel JRJP, Huijmans JE, Koolen SLW, Hendrikx JJMA, de Blois E. Hooijman EL, et al. EJNMMI Radiopharm Chem. 2022 Nov 4;7(1):29. doi: 10.1186/s41181-022-00181-0. EJNMMI Radiopharm Chem. 2022. PMID: 36333648 Free PMC article.
133 results