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Sorafenib and dacarbazine as first-line therapy for advanced melanoma: phase I and open-label phase II studies.
Eisen T, Marais R, Affolter A, Lorigan P, Robert C, Corrie P, Ottensmeier C, Chevreau C, Chao D, Nathan PD, Jouary T, Harries M, Negrier S, Montegriffo E, Ahmad T, Gibbens I, James MG, Strauss UP, Prendergast S, Gore ME. Eisen T, et al. Among authors: marais r. Br J Cancer. 2011 Jul 26;105(3):353-9. doi: 10.1038/bjc.2011.257. Epub 2011 Jul 12. Br J Cancer. 2011. PMID: 21750549 Free PMC article. Clinical Trial.
Sorafenib in advanced melanoma: a Phase II randomised discontinuation trial analysis.
Eisen T, Ahmad T, Flaherty KT, Gore M, Kaye S, Marais R, Gibbens I, Hackett S, James M, Schuchter LM, Nathanson KL, Xia C, Simantov R, Schwartz B, Poulin-Costello M, O'Dwyer PJ, Ratain MJ. Eisen T, et al. Among authors: marais r. Br J Cancer. 2006 Sep 4;95(5):581-6. doi: 10.1038/sj.bjc.6603291. Epub 2006 Aug 1. Br J Cancer. 2006. PMID: 16880785 Free PMC article. Clinical Trial.
Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma.
Girotti MR, Pedersen M, Sanchez-Laorden B, Viros A, Turajlic S, Niculescu-Duvaz D, Zambon A, Sinclair J, Hayes A, Gore M, Lorigan P, Springer C, Larkin J, Jorgensen C, Marais R. Girotti MR, et al. Among authors: marais r. Cancer Discov. 2013 Feb;3(2):158-67. doi: 10.1158/2159-8290.CD-12-0386. Epub 2012 Dec 14. Cancer Discov. 2013. PMID: 23242808 Free PMC article.
Distinct subclonal tumour responses to therapy revealed by circulating cell-free DNA.
Gremel G, Lee RJ, Girotti MR, Mandal AK, Valpione S, Garner G, Ayub M, Wood S, Rothwell DG, Fusi A, Wallace A, Brady G, Dive C, Dhomen N, Lorigan P, Marais R. Gremel G, et al. Among authors: marais r. Ann Oncol. 2016 Oct;27(10):1959-65. doi: 10.1093/annonc/mdw278. Epub 2016 Aug 8. Ann Oncol. 2016. PMID: 27502704 Free PMC article.
260 results