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A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth.
Mita H, Toyota M, Aoki F, Akashi H, Maruyama R, Sasaki Y, Suzuki H, Idogawa M, Kashima L, Yanagihara K, Fujita M, Hosokawa M, Kusano M, Sabau SV, Tatsumi H, Imai K, Shinomura Y, Tokino T. Mita H, et al. Among authors: shinomura y. BMC Cancer. 2009 Jun 23;9:198. doi: 10.1186/1471-2407-9-198. BMC Cancer. 2009. PMID: 19545448 Free PMC article.
Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma.
Nojima M, Maruyama R, Yasui H, Suzuki H, Maruyama Y, Tarasawa I, Sasaki Y, Asaoku H, Sakai H, Hayashi T, Mori M, Imai K, Tokino T, Ishida T, Toyota M, Shinomura Y. Nojima M, et al. Among authors: shinomura y. Clin Cancer Res. 2009 Jul 1;15(13):4356-64. doi: 10.1158/1078-0432.CCR-08-3336. Epub 2009 Jun 23. Clin Cancer Res. 2009. PMID: 19549772
Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect.
Suzuki H, Yamamoto E, Nojima M, Kai M, Yamano HO, Yoshikawa K, Kimura T, Kudo T, Harada E, Sugai T, Takamaru H, Niinuma T, Maruyama R, Yamamoto H, Tokino T, Imai K, Toyota M, Shinomura Y. Suzuki H, et al. Among authors: shinomura y. Carcinogenesis. 2010 Dec;31(12):2066-73. doi: 10.1093/carcin/bgq203. Epub 2010 Oct 5. Carcinogenesis. 2010. PMID: 20924086
A novel correlation between LINE-1 hypomethylation and the malignancy of gastrointestinal stromal tumors.
Igarashi S, Suzuki H, Niinuma T, Shimizu H, Nojima M, Iwaki H, Nobuoka T, Nishida T, Miyazaki Y, Takamaru H, Yamamoto E, Yamamoto H, Tokino T, Hasegawa T, Hirata K, Imai K, Toyota M, Shinomura Y. Igarashi S, et al. Among authors: shinomura y. Clin Cancer Res. 2010 Nov 1;16(21):5114-23. doi: 10.1158/1078-0432.CCR-10-0581. Epub 2010 Oct 26. Clin Cancer Res. 2010. PMID: 20978145
Epigenetic alteration of DNA in mucosal wash fluid predicts invasiveness of colorectal tumors.
Kamimae S, Yamamoto E, Yamano HO, Nojima M, Suzuki H, Ashida M, Hatahira T, Sato A, Kimura T, Yoshikawa K, Harada T, Hayashi S, Takamaru H, Maruyama R, Kai M, Nishiwaki M, Sugai T, Sasaki Y, Tokino T, Shinomura Y, Imai K, Toyota M. Kamimae S, et al. Among authors: shinomura y. Cancer Prev Res (Phila). 2011 May;4(5):674-83. doi: 10.1158/1940-6207.CAPR-10-0214. Cancer Prev Res (Phila). 2011. PMID: 21543345
399 results