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196 results

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Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors.
Goodman KB, Bury MJ, Cheung M, Cichy-Knight MA, Dowdell SE, Dunn AK, Lee D, Lieby JA, Moore ML, Scherzer DA, Sha D, Suarez DP, Murphy DJ, Harpel MR, Manas ES, McNulty DE, Annan RS, Matico RE, Schwartz BK, Trill JJ, Sweitzer TD, Wang DY, Keller PM, Krawiec JA, Jaye MC. Goodman KB, et al. Among authors: keller pm. Bioorg Med Chem Lett. 2009 Jan 1;19(1):27-30. doi: 10.1016/j.bmcl.2008.11.033. Epub 2008 Nov 14. Bioorg Med Chem Lett. 2009. PMID: 19058966
Potent and selective nonpeptide inhibitors of caspases 3 and 7.
Lee D, Long SA, Murray JH, Adams JL, Nuttall ME, Nadeau DP, Kikly K, Winkler JD, Sung CM, Ryan MD, Levy MA, Keller PM, DeWolf WE Jr. Lee D, et al. Among authors: keller pm. J Med Chem. 2001 Jun 7;44(12):2015-26. doi: 10.1021/jm0100537. J Med Chem. 2001. PMID: 11384246
Indole naphthyridinones as inhibitors of bacterial enoyl-ACP reductases FabI and FabK.
Seefeld MA, Miller WH, Newlander KA, Burgess WJ, DeWolf WE Jr, Elkins PA, Head MS, Jakas DR, Janson CA, Keller PM, Manley PJ, Moore TD, Payne DJ, Pearson S, Polizzi BJ, Qiu X, Rittenhouse SF, Uzinskas IN, Wallis NG, Huffman WF. Seefeld MA, et al. Among authors: keller pm. J Med Chem. 2003 Apr 24;46(9):1627-35. doi: 10.1021/jm0204035. J Med Chem. 2003. PMID: 12699381
Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI).
Miller WH, Seefeld MA, Newlander KA, Uzinskas IN, Burgess WJ, Heerding DA, Yuan CC, Head MS, Payne DJ, Rittenhouse SF, Moore TD, Pearson SC, Berry V, DeWolf WE Jr, Keller PM, Polizzi BJ, Qiu X, Janson CA, Huffman WF. Miller WH, et al. Among authors: keller pm. J Med Chem. 2002 Jul 18;45(15):3246-56. doi: 10.1021/jm020050+. J Med Chem. 2002. PMID: 12109908
Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality.
Lee D, Long SA, Adams JL, Chan G, Vaidya KS, Francis TA, Kikly K, Winkler JD, Sung CM, Debouck C, Richardson S, Levy MA, DeWolf WE Jr, Keller PM, Tomaszek T, Head MS, Ryan MD, Haltiwanger RC, Liang PH, Janson CA, McDevitt PJ, Johanson K, Concha NO, Chan W, Abdel-Meguid SS, Badger AM, Lark MW, Nadeau DP, Suva LJ, Gowen M, Nuttall ME. Lee D, et al. Among authors: keller pm. J Biol Chem. 2000 May 26;275(21):16007-14. doi: 10.1074/jbc.275.21.16007. J Biol Chem. 2000. PMID: 10821855 Free article.
A substrate combinatorial array for caspases.
Lee D, Adams JL, Brandt M, DeWolf WE Jr, Keller PM, Levy MA. Lee D, et al. Among authors: keller pm. Bioorg Med Chem Lett. 1999 Jun 21;9(12):1667-72. doi: 10.1016/s0960-894x(99)00260-7. Bioorg Med Chem Lett. 1999. PMID: 10397497
Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4-b]indoles as potential antibacterial agents.
Seefeld MA, Miller WH, Newlander KA, Burgess WJ, Payne DJ, Rittenhouse SF, Moore TD, DeWolf WE Jr, Keller PM, Qiu X, Janson CA, Vaidya K, Fosberry AP, Smyth MG, Jaworski DD, Slater-Radosti C, Huffman WF. Seefeld MA, et al. Among authors: keller pm. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2241-4. doi: 10.1016/s0960-894x(01)00405-x. Bioorg Med Chem Lett. 2001. PMID: 11527706
196 results