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Page 1
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis.
Quivoron C, Couronné L, Della Valle V, Lopez CK, Plo I, Wagner-Ballon O, Do Cruzeiro M, Delhommeau F, Arnulf B, Stern MH, Godley L, Opolon P, Tilly H, Solary E, Duffourd Y, Dessen P, Merle-Beral H, Nguyen-Khac F, Fontenay M, Vainchenker W, Bastard C, Mercher T, Bernard OA. Quivoron C, et al. Among authors: mercher t. Cancer Cell. 2011 Jul 12;20(1):25-38. doi: 10.1016/j.ccr.2011.06.003. Epub 2011 Jun 30. Cancer Cell. 2011. PMID: 21723201 Free article.
A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.
Bernard OA, Busson-LeConiat M, Ballerini P, Mauchauffé M, Della Valle V, Monni R, Nguyen Khac F, Mercher T, Penard-Lacronique V, Pasturaud P, Gressin L, Heilig R, Daniel MT, Lessard M, Berger R. Bernard OA, et al. Among authors: mercher t. Leukemia. 2001 Oct;15(10):1495-504. doi: 10.1038/sj.leu.2402249. Leukemia. 2001. PMID: 11587205
Recurrence of OTT-MAL fusion in t(1;22) of infant AML-M7.
Mercher T, Busson-Le Coniat M, Nguyen Khac F, Ballerini P, Mauchauffé M, Bui H, Pellegrino B, Radford I, Valensi F, Mugneret F, Dastugue N, Bernard OA, Berger R. Mercher T, et al. Genes Chromosomes Cancer. 2002 Jan;33(1):22-8. doi: 10.1002/gcc.1208. Genes Chromosomes Cancer. 2002. PMID: 11746984
Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export.
Hiriart E, Gruffat H, Buisson M, Mikaelian I, Keppler S, Meresse P, Mercher T, Bernard OA, Sergeant A, Manet E. Hiriart E, et al. Among authors: mercher t. J Biol Chem. 2005 Nov 4;280(44):36935-45. doi: 10.1074/jbc.M501725200. Epub 2005 Aug 29. J Biol Chem. 2005. PMID: 16129689 Free article.
Ott1(Rbm15) has pleiotropic roles in hematopoietic development.
Raffel GD, Mercher T, Shigematsu H, Williams IR, Cullen DE, Akashi K, Bernard OA, Gilliland DG. Raffel GD, et al. Among authors: mercher t. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):6001-6. doi: 10.1073/pnas.0609041104. Epub 2007 Mar 21. Proc Natl Acad Sci U S A. 2007. PMID: 17376872 Free PMC article.
The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model.
Mercher T, Raffel GD, Moore SA, Cornejo MG, Baudry-Bluteau D, Cagnard N, Jesneck JL, Pikman Y, Cullen D, Williams IR, Akashi K, Shigematsu H, Bourquin JP, Giovannini M, Vainchenker W, Levine RL, Lee BH, Bernard OA, Gilliland DG. Mercher T, et al. J Clin Invest. 2009 Apr;119(4):852-64. doi: 10.1172/JCI35901. Epub 2009 Mar 16. J Clin Invest. 2009. PMID: 19287095 Free PMC article.
[In cauda venenum or the importance of TET(2)].
Mercher T, Quivoron C, Couronné L, Vainchenker W, Bastard C, Bernard OA. Mercher T, et al. Med Sci (Paris). 2011 Dec;27(12):1064-6. doi: 10.1051/medsci/20112712009. Epub 2011 Dec 23. Med Sci (Paris). 2011. PMID: 22192742 Free article. French. No abstract available.
77 results