Chen FH - Search Results

1

Combination of pharmacophore model development and binding mode analyses: identification of ligand features essential for IκB kinase-beta (IKKβ) inhibitors and virtual screening based on it.

Sun HP, Zhu J, Chen FH, Zhang SL, Zhang Y, You QD. Sun HP, et al. Among authors: chen fh. Eur J Med Chem. 2011 Sep;46(9):3942-52. doi: 10.1016/j.ejmech.2011.05.066. Epub 2011 Jun 25. Eur J Med Chem. 2011. PMID: 21708416

2

Isolation and characterization of cancer stem like cells in human glioblastoma cell lines.

Qiang L, Yang Y, Ma YJ, Chen FH, Zhang LB, Liu W, Qi Q, Lu N, Tao L, Wang XT, You QD, Guo QL. Qiang L, et al. Among authors: chen fh. Cancer Lett. 2009 Jun 28;279(1):13-21. doi: 10.1016/j.canlet.2009.01.016. Epub 2009 Feb 15. Cancer Lett. 2009. PMID: 19232461

3

Reactive oxygen species-mitochondria pathway involved in LYG-202-induced apoptosis in human hepatocellular carcinoma HepG(2) cells.

Chen FH, Zhang LB, Qiang L, Yang Z, Wu T, Zou MJ, Tao L, You QD, Li ZY, Yang Y, Guo QL. Chen FH, et al. Cancer Lett. 2010 Oct 1;296(1):96-105. doi: 10.1016/j.canlet.2010.04.004. Epub 2010 May 23. Cancer Lett. 2010. PMID: 20580989

4

DHF-18, a new synthetic flavonoid, induced a mitochondrial-mediated apoptosis of hepatocarcinoma cells in vivo and in vitro.

Zhang LB, Qiang L, Chen FH, Wu T, Rong JJ, Zhao Q, Zou MJ, Yang Z, You QD, Li ZY, Wu YL, Guo QL. Zhang LB, et al. Among authors: chen fh. Eur J Pharmacol. 2011 Jan 25;651(1-3):33-40. doi: 10.1016/j.ejphar.2010.10.067. Epub 2010 Nov 18. Eur J Pharmacol. 2011. PMID: 21093431

5

Studies on gambogic acid (IV): Exploring structure-activity relationship with IκB kinase-beta (IKKβ).

Sun H, Chen F, Wang X, Liu Z, Yang Q, Zhang X, Zhu J, Qiang L, Guo Q, You Q. Sun H, et al. Eur J Med Chem. 2012 May;51:110-23. doi: 10.1016/j.ejmech.2012.02.029. Epub 2012 Mar 3. Eur J Med Chem. 2012. PMID: 22472167

6

LYG-202 augments tumor necrosis factor-α-induced apoptosis via attenuating casein kinase 2-dependent nuclear factor-κB pathway in HepG2 cells.

Chen FH, Lu N, Zhang HW, Zhao L, He LC, Sun HP, You QD, Li ZY, Guo QL. Chen FH, et al. Mol Pharmacol. 2012 Nov;82(5):958-71. doi: 10.1124/mol.112.079848. Epub 2012 Aug 21. Mol Pharmacol. 2012. PMID: 22909797

7

Cytotoxicity profile of novel sterically hindered platinum(II) complexes with (1R,2R)-N(1),N(2)-dibutyl-1,2-diaminocyclohexane.

Zhang H, Gou S, Zhao J, Chen F, Xu G, Liu X. Zhang H, et al. Eur J Med Chem. 2015;96:187-95. doi: 10.1016/j.ejmech.2015.04.019. Epub 2015 Apr 8. Eur J Med Chem. 2015. PMID: 25874342

8

Toward overcoming cisplatin resistance via sterically hindered platinum(II) complexes.

Yu H, Gou S, Wang Z, Chen F, Fang L. Yu H, et al. Eur J Med Chem. 2016 May 23;114:141-52. doi: 10.1016/j.ejmech.2016.02.060. Epub 2016 Feb 27. Eur J Med Chem. 2016. PMID: 26974381

9

Structure-Based Pharmacophore Modeling from Multicomplex: a Comprehensive Pharmacophore Generation of Protein Kinase CK2 and Virtual Screening Based on it for Novel Inhibitors.

Sun HP, Zhu J, Chen FH, You QD. Sun HP, et al. Among authors: chen fh. Mol Inform. 2011 Jun;30(6-7):579-92. doi: 10.1002/minf.201000178. Epub 2011 May 25. Mol Inform. 2011. PMID: 27467158

10

Conjugation of platinum(IV) complexes with chlorambucil to overcome cisplatin resistance via a "joint action" mode toward DNA.

Qin X, Fang L, Chen F, Gou S. Qin X, et al. Eur J Med Chem. 2017 Sep 8;137:167-175. doi: 10.1016/j.ejmech.2017.05.056. Epub 2017 May 28. Eur J Med Chem. 2017. PMID: 28586717

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