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The amount of calcium-deficient hexagonal hydroxyapatite in aortic valves is influenced by gender and associated with genetic polymorphisms in patients with severe calcific aortic stenosis.
Ortlepp JR, Schmitz F, Mevissen V, Weiss S, Huster J, Dronskowski R, Langebartels G, Autschbach R, Zerres K, Weber C, Hanrath P, Hoffmann R. Ortlepp JR, et al. Among authors: autschbach r. Eur Heart J. 2004 Mar;25(6):514-22. doi: 10.1016/j.ehj.2003.09.006. Eur Heart J. 2004. PMID: 15039132
APOE alleles are not associated with calcific aortic stenosis.
Ortlepp JR, Pillich M, Mevissen V, Krantz C, Kimmel M, Autschbach R, Langebartels G, Erdmann J, Hoffmann R, Zerres K. Ortlepp JR, et al. Among authors: autschbach r. Heart. 2006 Oct;92(10):1463-6. doi: 10.1136/hrt.2005.075317. Epub 2006 Apr 10. Heart. 2006. PMID: 16606866 Free PMC article.
Lower serum calcium levels are associated with greater calcium hydroxyapatite deposition in native aortic valves of male patients with severe calcific aortic stenosis.
Ortlepp JR, Pillich M, Schmitz F, Mevissen V, Koos R, Weiss S, Stork L, Dronskowski R, Langebartels G, Autschbach R, Brandenburg V, Woodruff S, Kaden JJ, Hoffmann R. Ortlepp JR, et al. Among authors: autschbach r. J Heart Valve Dis. 2006 Jul;15(4):502-8. J Heart Valve Dis. 2006. PMID: 16901043
244 results