Roman HB - Search Results

1

Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide.

Ueki I, Roman HB, Valli A, Fieselmann K, Lam J, Peters R, Hirschberger LL, Stipanuk MH. Ueki I, et al. Among authors: roman hb. Am J Physiol Endocrinol Metab. 2011 Oct;301(4):E668-84. doi: 10.1152/ajpendo.00151.2011. Epub 2011 Jun 21. Am J Physiol Endocrinol Metab. 2011. PMID: 21693692 Free PMC article.

2

Extrahepatic tissues compensate for loss of hepatic taurine synthesis in mice with liver-specific knockout of cysteine dioxygenase.

Ueki I, Roman HB, Hirschberger LL, Junior C, Stipanuk MH. Ueki I, et al. Among authors: roman hb. Am J Physiol Endocrinol Metab. 2012 May 1;302(10):E1292-9. doi: 10.1152/ajpendo.00589.2011. Epub 2012 Mar 13. Am J Physiol Endocrinol Metab. 2012. PMID: 22414809 Free PMC article.

3

The cysteine dioxgenase knockout mouse: altered cysteine metabolism in nonhepatic tissues leads to excess H2S/HS(-) production and evidence of pancreatic and lung toxicity.

Roman HB, Hirschberger LL, Krijt J, Valli A, Kožich V, Stipanuk MH. Roman HB, et al. Antioxid Redox Signal. 2013 Oct 20;19(12):1321-36. doi: 10.1089/ars.2012.5010. Epub 2013 Mar 19. Antioxid Redox Signal. 2013. PMID: 23350603 Free PMC article.

4

Upregulation of capacity for glutathione synthesis in response to amino acid deprivation: regulation of glutamate-cysteine ligase subunits.

Sikalidis AK, Mazor KM, Lee JI, Roman HB, Hirschberger LL, Stipanuk MH. Sikalidis AK, et al. Among authors: roman hb. Amino Acids. 2014 May;46(5):1285-96. doi: 10.1007/s00726-014-1687-1. Epub 2014 Feb 21. Amino Acids. 2014. PMID: 24557597 Free PMC article.

5

Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate.

Jurkowska H, Roman HB, Hirschberger LL, Sasakura K, Nagano T, Hanaoka K, Krijt J, Stipanuk MH. Jurkowska H, et al. Among authors: roman hb. Amino Acids. 2014 May;46(5):1353-65. doi: 10.1007/s00726-014-1700-8. Epub 2014 Mar 8. Amino Acids. 2014. PMID: 24609271 Free PMC article.

6

Propargylglycine inhibits hypotaurine/taurine synthesis and elevates cystathionine and homocysteine concentrations in primary mouse hepatocytes.

Jurkowska H, Stipanuk MH, Hirschberger LL, Roman HB. Jurkowska H, et al. Among authors: roman hb. Amino Acids. 2015 Jun;47(6):1215-23. doi: 10.1007/s00726-015-1948-7. Epub 2015 Mar 13. Amino Acids. 2015. PMID: 25772816 Free PMC article.

7

Insights into Taurine Synthesis and Function Based on Studies with Cysteine Dioxygenase (CDO1) Knockout Mice.

Stipanuk MH, Jurkowska H, Roman HB, Niewiadomski J, Hirschberger LL. Stipanuk MH, et al. Among authors: roman hb. Adv Exp Med Biol. 2015;803:29-39. doi: 10.1007/978-3-319-15126-7_3. Adv Exp Med Biol. 2015. PMID: 25833485 No abstract available.

8

Downregulation of hepatic betaine:homocysteine methyltransferase (BHMT) expression in taurine-deficient mice is reversed by taurine supplementation in vivo.

Jurkowska H, Niewiadomski J, Hirschberger LL, Roman HB, Mazor KM, Liu X, Locasale JW, Park E, Stipanuk MH. Jurkowska H, et al. Among authors: roman hb. Amino Acids. 2016 Mar;48(3):665-676. doi: 10.1007/s00726-015-2108-9. Epub 2015 Oct 20. Amino Acids. 2016. PMID: 26481005 Free PMC article.

9

Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice.

Niewiadomski J, Zhou JQ, Roman HB, Liu X, Hirschberger LL, Locasale JW, Stipanuk MH. Niewiadomski J, et al. Among authors: roman hb. Ann N Y Acad Sci. 2016 Jan;1363(1):99-115. doi: 10.1111/nyas.13021. Ann N Y Acad Sci. 2016. PMID: 26995761 Free PMC article.

10

Identification of Taurine-Responsive Genes in Murine Liver Using the Cdo1-Null Mouse Model.

Stipanuk MH, Jurkowska H, Niewiadomski J, Mazor KM, Roman HB, Hirschberger LL. Stipanuk MH, et al. Among authors: roman hb. Adv Exp Med Biol. 2017;975 Pt 1:475-495. doi: 10.1007/978-94-024-1079-2_38. Adv Exp Med Biol. 2017. PMID: 28849476

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