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Probes for narcotic receptor mediated phenomena. 43. Synthesis of the ortho-a and para-a, and improved synthesis and optical resolution of the ortho-b and para-b oxide-bridged phenylmorphans: compounds with moderate to low opioid-receptor affinity.
Li F, Folk JE, Cheng K, Kurimura M, Deck JA, Deschamps JR, Rothman RB, Dersch CM, Jacobson AE, Rice KC. Li F, et al. Among authors: kurimura m. Bioorg Med Chem. 2011 Jul 15;19(14):4330-7. doi: 10.1016/j.bmc.2011.05.035. Epub 2011 May 24. Bioorg Med Chem. 2011. PMID: 21684752 Free PMC article.
Probes for narcotic receptor mediated phenomena. 37. Synthesis and opioid binding affinity of the final pair of oxide-bridged phenylmorphans, the ortho- and para-b-isomers and their N-phenethyl analogues, and the synthesis of the N-phenethyl analogues of the ortho- and para-d-isomers.
Kurimura M, Liu H, Sulima A, Hashimoto A, Przybyl AK, Ohshima E, Kodato S, Deschamps JR, Dersch CM, Rothman RB, Lee YS, Jacobson AE, Rice KC. Kurimura M, et al. J Med Chem. 2008 Dec 25;51(24):7866-81. doi: 10.1021/jm800913d. J Med Chem. 2008. PMID: 19053757 Free PMC article.
Characterization of orally active nonpeptide vasopressin V(2) receptor agonist. Synthesis and biological evaluation of both the (5R)- and (5S)-enantioisomers of 2-[1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin- 5-yl]-N-isopropylacetamide.
Kondo K, Kan K, Tanada Y, Bando M, Shinohara T, Kurimura M, Ogawa H, Nakamura S, Hirano T, Yamamura Y, Kido M, Mori T, Tominaga M. Kondo K, et al. Among authors: kurimura m. J Med Chem. 2002 Aug 15;45(17):3805-8. doi: 10.1021/jm020133q. J Med Chem. 2002. PMID: 12166952
30 results