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Page 1
Viral serpin therapeutics from concept to clinic.
Chen H, Zheng D, Davids J, Bartee MY, Dai E, Liu L, Petrov L, Macaulay C, Thoburn R, Sobel E, Moyer R, McFadden G, Lucas A. Chen H, et al. Among authors: lucas a. Methods Enzymol. 2011;499:301-29. doi: 10.1016/B978-0-12-386471-0.00015-8. Methods Enzymol. 2011. PMID: 21683260 Free PMC article. Review.
10 M-T7: measuring chemokine-modulating activity.
Bartee MY, Dai E, Liu L, Munuswamy-Ramanujam G, Macaulay C, McIvor D, McFadden G, Lucas AR. Bartee MY, et al. Methods Enzymol. 2009;460:209-28. doi: 10.1016/S0076-6879(09)05210-0. Methods Enzymol. 2009. PMID: 19446727
The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics.
Lucas A, Liu L, Dai E, Bot I, Viswanathan K, Munuswamy-Ramunujam G, Davids JA, Bartee MY, Richardson J, Christov A, Wang H, Macaulay C, Poznansky M, Zhong R, Miller L, Biessen E, Richardson M, Sullivan C, Moyer R, Hatton M, Lomas DA, McFadden G. Lucas A, et al. Adv Exp Med Biol. 2009;666:132-56. doi: 10.1007/978-1-4419-1601-3_11. Adv Exp Med Biol. 2009. PMID: 20054981 Review.
Myxomavirus-derived serpin prolongs survival and reduces inflammation and hemorrhage in an unrelated lethal mouse viral infection.
Chen H, Zheng D, Abbott J, Liu L, Bartee MY, Long M, Davids J, Williams J, Feldmann H, Strong J, Grau KR, Tibbetts S, Macaulay C, McFadden G, Thoburn R, Lomas DA, Spinale FG, Virgin HW, Lucas A. Chen H, et al. Among authors: lucas a. Antimicrob Agents Chemother. 2013 Sep;57(9):4114-27. doi: 10.1128/AAC.02594-12. Epub 2013 Jun 17. Antimicrob Agents Chemother. 2013. PMID: 23774438 Free PMC article.
The serpin solution; targeting thrombotic and thrombolytic serine proteases in inflammation.
Chen H, Davids JA, Zheng D, Bryant M, Bot I, van Berckel TJ, Biessen E, Pepine C, Ryman K, Progulski-Fox A, Kesavalu L, Moyer R, McFadden G, Lucas A. Chen H, et al. Among authors: lucas a. Cardiovasc Hematol Disord Drug Targets. 2013 Aug;13(2):99-110. doi: 10.2174/1871529x11313020003. Cardiovasc Hematol Disord Drug Targets. 2013. PMID: 23987998 Review.
Serpins for diagnosis and therapy in cancer.
Zheng D, Chen H, Davids J, Bryant M, Lucas A. Zheng D, et al. Among authors: lucas a. Cardiovasc Hematol Disord Drug Targets. 2013 Aug;13(2):123-32. doi: 10.2174/1871529x11313020005. Cardiovasc Hematol Disord Drug Targets. 2013. PMID: 23988000 Review.
Viral TNF inhibitors as potential therapeutics.
Rahman MM, Lucas AR, McFadden G. Rahman MM, et al. Adv Exp Med Biol. 2009;666:64-77. doi: 10.1007/978-1-4419-1601-3_5. Adv Exp Med Biol. 2009. PMID: 20054975 Review.
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