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A novel small molecule, (E)-5-(2,4-di-tert-butyl-6-((2,4-dioxothiazolidin-5-ylidene)methyl)phenyl)-5'-methyl-7,7'-dimethoxy-4,4'-bibenzo[d][1,3]dioxole-5,5'-dicarboxylate (7k), alleviates the development of D-galactosamine/lipopolysaccharide-induced acute liver failure by inhibiting macrophage infiltration and regulating cytokine expression.
Deng C, Liu J, Wang G, Ma L, Xie C, Wang X, Li X, Chen L. Deng C, et al. Among authors: liu j. J Pharmacol Exp Ther. 2012 Apr;341(1):146-55. doi: 10.1124/jpet.111.189498. Epub 2012 Jan 11. J Pharmacol Exp Ther. 2012. PMID: 22238210
Identification of honokiol metabolites in rats by the method of stable isotope cluster technique and ultra-high performance liquid chromatography/quadrupole-time-of-flight mass spectrometry.
Lai H, Tang M, Liu J, Dong Y, Qiu N, Li S, Ma L, Yang J, Song H, Zhang Y, Peng A, Chen L. Lai H, et al. Among authors: liu j. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Jul 15;931:157-63. doi: 10.1016/j.jchromb.2013.05.020. Epub 2013 May 28. J Chromatogr B Analyt Technol Biomed Life Sci. 2013. PMID: 23792368
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